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TranscriptomicsIGR_MITF_STUDY_BBRB
A recent study of the characteristics of coexisting melanoma and renal cell carcinoma RCC in the same patients supports a genetic predisposition underlying the association between these two cancers. The microphthalmia associated transcription factor (MITF) was proposed to act as a melanoma oncogene;...
ORGANISM(S): Homo sapiens 
2011-09-03 | E-TABM-1198 | biostudies-arrayexpress
TranscriptomicsGene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing.
Purpose: Calcific aortic valve stenosis (AS) is a fatal disease with currently no medical therapy. Some genes were associated with AS, but the genetic architecture of the disease has yet to be discovered. The objective of this study was to combine genome-wide association studies (GWAS) and gene expr...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-55492 | biostudies-arrayexpress
TranscriptomicsIGR_PBI_SOCS1_GE_JP
Suppressor of cytokine signaling (SOCS1) is an inducible negative regulator of cytokine signaling. SOCS1 is expressed in normal colonic epithelium and colon adenocarcinomas. However, the levels of SOCS1 decreased during progression of colon adenocarcinomas, the lowest level being found in the more ...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-MTAB-1742 | biostudies-arrayexpress
TranscriptomicsIGR_MEGACARYOCYTES_STUDY_OB
The molecular bases of cellular changes that occur during ontogeny of human megakaryopoiesis remained unknown. We performed global gene expression profiling of pure populations of megakaryocytes (MK) derived from ES cells (MKES), fetal liver (MKFL), cord blood (MKCB) and adult blood (MKAD). A close ...
ORGANISM(S): Homo sapiens 
2013-06-24 | E-MTAB-1452 | biostudies-arrayexpress
UnknownTreat stroke to target trial design: First trial comparing two LDL targets in patients with atherothrombotic strokes.
Not available
S-EPMC6960693 | biostudies-literature
UnknownDevelopment and validation of a French questionnaire concerning patients' perspectives of the quality of palliative care: the QUALI-PALLI-Patient.
Not available
S-EPMC6369559 | biostudies-literature
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
TranscriptomicsExpression data from Escherichia coli O157:H7, strain EDL933, cultivated in caecal content of rats associated with the human intestinal microbiota
The human intestinal microbiota associated with rats produces in vivo a soluble(s) factor(s) that down-regulates the expression of genes encoding for the Shiga toxin II in E. coli O157:H7. The Shiga toxin II is one of the major virulence factors of E. coli enterohemorragic leading to the deadly hemo...
ORGANISM(S): Escherichia coli O157:H7 str. EDL933 
2013-09-10 | E-GEOD-37095 | biostudies-arrayexpress
UnknownLarge-scale gene discovery in the pea aphid Acyrthosiphon pisum (Hemiptera).
Not available
S-EPMC1557754 | biostudies-literature
TranscriptomicsTranscripts coding MHC I-associated peptides are enriched in microRNA-binding sites
MHC I-peptides (MIPs) play an essential role in normal homeostasis and diverse pathological conditions. MIPs derive mainly from defective ribosomal products (DRiPs), a subset of nascent proteins that fail to achieve a proper conformation and whose physical nature remains elusive. We used high-throug...
ORGANISM(S): Homo sapiens 
2012-03-25 | E-GEOD-35319 | biostudies-arrayexpress
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