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ProteomicsMethod development for simplified High-Throughput Plasma Proteomics
We developed a simplified proteomics sample preparation method that increased the sensitivity and reproducibility of large-scale plasma samples. Peptide loss was reduced while sensitivity was increased by eliminating the peptide clean-up step and using disposable trap column tips. The simplified Hig...
ORGANISM(S): Homo sapiens (Human) 
2023-04-03 | PXD038669 | Pride
Shtpp Simplified high-throughput plasma proteomics 
ProteomicsA simplified and efficient extracellular vesicles-based proteomics strategy for early diagnosis of colorectal cancer
In this work, we have developed a simplified, fast and efficient EVs-based proteomics strategy to enable biomarker discovery for early diagnosis of CRC. By covalent conjugation of an EV-targeting probe, DSPE, to agarose beads, we achieved one-step enrichment of EVs from plasma fluids in 10 minutes w...
ORGANISM(S): Homo Sapiens 
PXD054231 |
UnknownA Streamlined High-Throughput Plasma Proteomics Platform for Clinical Proteomics with Improved Proteome Coverage, Reproducibility, and Robustness.
Not available
S-EPMC10080683 | biostudies-literature
ProteomicsA novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics
To further integrate mass spectrometry (MS)-based proteomics into biomedical research and especially into clinical settings, high throughput and robustness are essential requirements. They are largely met in high-flow rate chromatographic systems for small molecules but these are not sufficiently se...
ORGANISM(S): Homo sapiens (Human) 
2018-08-16 | PXD010393 | Pride
Clinic Plasma Liquid chromatography 
UnknownSimultaneous Immunoglobulin A and G Glycopeptide Profiling for High-Throughput Applications.
Not available
S-EPMC7252899 | biostudies-literature
UnknownAutomated Plasma Glycomics with Linkage-Specific Sialic Acid Esterification and Ultrahigh Resolution MS.
Not available
S-EPMC6209171 | biostudies-literature
UnknownEarly detection of Ebola virus proteins in peripheral blood mononuclear cells from infected mice.
Not available
S-EPMC7077124 | biostudies-literature
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