Simpson A A AA - OmicsDI

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Unknown (345)
Transcriptomics (8)
Metabolomics (5)
Genomics (2)
Proteomics (2)

Organisms

Mus musculus (5)
Homo sapiens (5)
Caldicellulosiruptor kronotskyensis (1)
Rattus norvegicus (1)

Repository

biostudies-arrayexpress (9)
MetaboLights (5)
pride (2)
EGA (1)

Tissue

Liver (1)
Tendon (1)

Technology Type

Mass spectrometry (5)
Mass Spectrometry (2)
Shotgun proteomics (2)

Instrument Platform

Exactive (Thermo Scientific) (2)
GC-TOF-MS (1)
Gas Chromatography MS - (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2012 (4)
2020 (4)
2016 (3)
2011 (2)
2015 (1)
2013 (1)
2017 (1)

CHEBI ID

CHEBI:15756 (4)
CHEBI:16000 (4)
CHEBI:16196 (4)
CHEBI:16335 (4)
CHEBI:16449 (4)
CHEBI:16811 (4)
CHEBI:16865 (4)
CHEBI:17822 (4)
CHEBI:18186 (4)
CHEBI:22660 (4)
CHEBI:25017 (4)
CHEBI:25094 (4)
CHEBI:26986 (4)
CHEBI:27266 (4)
CHEBI:28044 (4)
CHEBI:28842 (4)
CHEBI:28897 (4)
CHEBI:30769 (4)
CHEBI:132194 (3)
CHEBI:14336 (3)
CHEBI:15428 (3)
CHEBI:15760 (3)
CHEBI:16010 (3)
CHEBI:16708 (3)
CHEBI:17053 (3)
CHEBI:17148 (3)
CHEBI:17191 (3)
CHEBI:17568 (3)
CHEBI:17754 (3)
CHEBI:17964 (3)

Metabolite Name

2-Piperidinecarboxylic acid, 1-(trimethylsilyl)-, trimethylsilyl ester (3)
Alpha-D-Mannopyranose, 1,2,3,4,6-pentakis-O-(trimethylsilyl)- (3)
Butanoic acid, 2,4-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester (3)
L-Aspartic acid, N-(trimethylsilyl)-, bis(trimethylsilyl) ester (3)
L-Isoleucine, N-(trimethylsilyl)-, trimethylsilyl ester (3)
N,O-Bis-(trimethylsilyl)-2-pyrrolidone carboxylic acid (3)
Nonadecane (3)
Pentadecane (3)
Phosphoric acid, bis(trimethylsilyl) 2,3-bis[(trimethylsilyl)oxy]propyl ester (3)
Pyridine, 3-trimethylsiloxy- (3)
Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-N-[2-[(trimethylsilyl)oxy]ethyl]- (3)
Silanamine, N-[2-[3,4-bis[(trimethylsilyl)oxy]phenyl]ethyl]-1,1,1-trimethyl-N-(trimethylsilyl)- (3)
Trimethylsilyl ether of glycerol (3)
4-(Trimethylsilyl)morpholine (2)
4-aminobutyric acid (2)
Adenosine (2)
Alanine (2)
Arabinofuranose, 1,2,3,5-tetrakis-O-(trimethylsilyl)- (2)
Aspartic acid (2)
Cyclopentanecarboxylic acid, 1-amino-, bis(trimethylsilyl) deriv. (2)
Cyclopentene, 3-methyl-1-(trimethylsilyloxy)- (2)
Eicosane (2)
Eicosane, 2-methyl- (2)
Gluconic acid (2)
Glutamine (2)
Glycine d5 (2)
Heptadecane (2)
Hexadecanoic acid (2)
L-Leucine, N-(trimethylsilyl)-, trimethylsilyl ester (2)
L-Tryptophan, N,1-bis(trimethylsilyl)-, trimethylsilyl ester (2)

Study type

Transcription profiling by RT-PCR (4)
Genotyping by array (1)
Comparative genomic hybridization by array (1)
Transcription profiling by array (1)
Methylation profiling by high throughput sequencing (1)
RNA-seq of coding RNA (1)

Release Date

2022 (43)
2020 (42)
2024 (41)
2023 (39)
2021 (39)
2025 (33)
2018 (18)
2015 (14)
2012 (11)
2017 (11)
2016 (9)
2011 (9)
2019 (9)
2013 (6)
2014 (6)
2010 (4)
2009 (3)
2004 (3)
2026 (2)
2005 (2)
2003 (2)
2002 (2)
2000 (2)
2006 (1)
2001 (1)
1998 (1)
1997 (1)

Lab affiliation

1 Department of Biochemistry and Molecular Biology, Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Clayton 3800, Australia. (1)
Comparative Biomedical Sciences Royal Veterinary College Royal College Street London NW1 0TU (1)

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Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence

There is an urgent need to develop novel antifungals to tackle the threat that fungal pathogens pose to human health. In this work, we have performed a thorough characterisation and validation of the promising target methionine synthase. We have uncovered that in Aspergillus fumigatus the absence of...

2020-10-15 | MTBLS1636 | MetaboLights

Contrasting amino acid profiles among permissive and non-permissive hosts of Candidatus Liberibacter asiaticus, putative causal agent of Huanglongbing.

Not available

S-EPMC5728503 | biostudies-literature

Metabolomic analysis of riboswitch containing E. coli recombinant expression system

In this study we have employed metabolomics approaches to understand the metabolic effects of producing enhanced green fluorescent protein (eGFP) as a recombinant protein in Escherichia coli cells. This metabolic burden analysis was performed against a number of recombinant expression systems and co...

2017-11-16 | MTBLS393 | MetaboLights

Restriction of essential amino acids dictates the systemic response to dietary protein dilution

Dietary protein dilution (DPD) promotes metabolic remodelling and health but the precise nutritional components driving this response remain elusive. Here we demonstrate that dietary amino acids (AA) are sufficient and necessary to drive the response to DPD. In particular, the restriction of dietary...

ORGANISM(S): Mus musculus (Mouse)

2020-06-15 | PXD018205 | Pride

Essential amino acids Thr biosynthetic

Comparisons of de novo transcriptome assemblers in diploid and polyploid species using peanut (Arachis spp.) RNA-Seq data.

Not available

S-EPMC4281230 | biostudies-literature

Whole Genome Association Study of Bipolar Disorder

The goal of the project is to identify genes that make individuals more susceptible to bipolar disorder (manic depressive illness) and to better understand the brain pathways involved in the disease.

Dataset versioning