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MetabolomicsTargeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
There is an urgent need to develop novel antifungals to tackle the threat that fungal pathogens pose to human health. In this work, we have performed a thorough characterisation and validation of the promising target methionine synthase. We have uncovered that in Aspergillus fumigatus the absence of...
2020-10-15 | MTBLS1636 | MetaboLights
MetabolomicsLipid biomarkers for algal resistance to viral infection in the ocean

Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has been reported for various phytoplankton species under laboratory conditions. Nevertheless, the occurrence of resi...

2023-06-12 | MTBLS3323 | MetaboLights
UnknownMaternal iodine status, intrauterine growth, birth outcomes and congenital anomalies in a UK birth cohort.
Not available
S-EPMC7288513 | biostudies-literature
UnknownSerial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease.
Not available
S-EPMC2677798 | biostudies-literature
UnknownPrenatal and Postpartum Maternal Iodide Intake from Diet and Supplements, Urinary Iodine and Thyroid Hormone Concentrations in a Region of the United Kingdom with Mild-to-Moderate Iodine Deficiency.
Not available
S-EPMC7830764 | biostudies-literature
UnknownMaternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder.
Not available
S-EPMC7718710 | biostudies-literature
UnknownEthnic variations in morbidity and mortality from lower respiratory tract infections: a retrospective cohort study.
Not available
S-EPMC4622271 | biostudies-literature
UnknownAdaptive electronics for photovoltaic, photoluminescent and photometric methods in power harvesting for wireless wearable sensors.
Not available
S-EPMC12217178 | biostudies-literature
UnknownEarly Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II): protocol for an observational study using linked Scottish national data.
Not available
S-EPMC7311023 | biostudies-literature
ProteomicsVariable Thresholds for Phosphorylation Targets of the ERK Signaling Pathway
Cell fates regulated by ERK/MAP kinases respond to different thresholds of signaling strength. In mammalian cells, conditions that activate ERK to submaximal levels are sufficient to sustain proliferation, survival and transformation, while stimuli that activate ERK to very high levels often lead t...
ORGANISM(S): Homo sapiens (Human) 
2026-02-25 | PXD071110 | Pride
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