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TranscriptomicsGene expression data from immortal and arsenite-transformed malignant prostate epithelial cells
The aim of this study was to determine how gene expression is changed after arsenite-induced malignant transformation of prostate epithelial cells. Gene expression from three distinct passages of untreated, immortal RWPE-1 cells was compared to three timepoints of arsenite-exposed RWPE-1 cells (CAsE...
ORGANISM(S): Homo sapiens 
2013-05-18 | E-GEOD-47047 | biostudies-arrayexpress
TranscriptomicsIntracellular and extracellular microRNAs expressed by HEK293T cells
MicroRNAs (miRNAs) are a class of small RNA molecules that regulate expression of specific mRNA targets. They can be released from cells, often encapsulated within extracellular vesicles (EVs), and therefore have the potential to mediate intercellular communication. It has been suggested that certai...
ORGANISM(S): Homo sapiens 
2012-06-25 | E-GEOD-38916 | biostudies-arrayexpress
TranscriptomicsPredicting the evolution of metastatic disease in breast cancer: results from 50 years of autopsies
This is a genomic analysis of breast cancer metastasis using array based CGH and is part of a large study investigating the patterns and evolution of metastases from breast cancer using autopsy material accumulated over the last 50 years from a single institution. The samples used in the genomic pro...
ORGANISM(S): Homo sapiens 
2013-11-11 | E-GEOD-46826 | biostudies-arrayexpress
UnknownDeveloping an Anti-Racism Tool Kit for Medical Education: A Pre-Clerkship Curriculum Audit.
Not available
S-EPMC12559637 | biostudies-literature
TranscriptomicsTranscription profiling of human fibroblasts synchronized and treated with 1.5 Gy irraditation to identify primary transcriptional regulation of cell-cycle-regulated genes upon DNA damage
The changes in global gene expression in response to DNA damage may derive from either direct induction or repression by transcriptional regulation or indirectly by synchronization of cells to specific cell cycle phases, such as G1 or G2. We developed a model that successfully estimated the express...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7075 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibroblasts subjected to DNA damage reveals ATM-dependent regulation of gene expression
The relationships between profiles of global gene expression and DNA damage checkpoint functions were studied in cells from patients with ataxia telangiectasia (AT). Three telomerase-expressing AT fibroblast lines displayed the expected hypersensitivity to ionizing radiation (IR) and defects in DNA...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6971 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human diploid fibroblasts after ionizing radiation damage
Cell cycle arrest and transcriptional responses to ionizing radiation (IR)-induced DNA damage were quantified in telomerase-expressing human diploid fibroblasts. Assays of clonal expansion established 1.5 Gy IR as the D0 dose in three fibroblast lines and this dose was used in all subsequent analyse...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6902 | biostudies-arrayexpress
OtherExtracellular remodelling during oncogenic Ras-induced epithelial-mesenchymal transition facilitates MDCK cell migration.
PeptideAtlas ID: PAe003680. Original data file: O070224-30.mgf. Data published as part of J Proteome Res. 2010 Feb 5;9(2):1007-19 . From the Abstract: {{i}}... To gain insights into extracellular mediators associated with EMT, we conducted an extensive proteomic analysis of the secretome from MDCK ...
ORGANISM(S): Dog, Canine_adenovirus, Canine_calicivirus, Canine_distemper_virus, Canine_minute_virus, Canine_oral_papillomavirus, Canine_papillomavirus_2, Canine_papillomavirus___3, Canine_papillomavirus___4, Canine_parvovirus 
GPM11210000341 | GPMDB
UnknownA Phase II study of autologous mesenchymal stromal cells and c-kit positive cardiac cells, alone or in combination, in patients with ischaemic heart failure: the CCTRN CONCERT-HF trial.
Not available
S-EPMC8357352 | biostudies-literature
TranscriptomicsTranscription profiling of human normal melanocytes and melamoma cell lines reveal defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression
Defects in DNA damage responses may underlie genetic instability and malignant progression in melanoma. Cultures of normal human melanocytes (NHMs) and melanoma lines were analyzed to determine whether global patterns of gene expression could predict the efficacy of DNA damage cell cycle checkpoints...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7469 | biostudies-arrayexpress
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