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TranscriptomicsPromoter capture Hi-C of human SGBS (Simpson-Golabi-Behmel syndrome preadipocyte) cells and iPSC-derived hypothalamic cells
To identify distal chromatin contacts between promoters and their putative regulatory elements in SGBS preadipocytes and hypothalamic arcuate-like neurons derived from iPSC, we performed Hi-C with a capture step to enrich the library for contacts involving promoters. Hi-C with a capture step was per...
ORGANISM(S): Homo sapiens 
2021-03-20 | E-MTAB-10200 | biostudies-arrayexpress
UnknownTelemedicine Use in Orthopaedic Surgery Varies by Race, Ethnicity, Primary Language, and Insurance Status.
Not available
S-EPMC8208394 | biostudies-literature
UnknownNutritional ecology beyond the individual: a conceptual framework for integrating nutrition and social interactions.
Not available
S-EPMC4342766 | biostudies-literature
TranscriptomicsIn situ promoter capture Hi-C data of differentiated SGBS human preadipocytes (days 0, 2, 8 and 16 of differentiation to adipocytes) and iPSC-derived hypothalamic neurons (days 12, 16 and 27 of differentiation)
Human SGBS preadipocytes were differentiated into adipocytes, and human iPSCs were differentiated into hypothalamic neurons. Cells were collected for in situ promoter capture Hi-C [PMID: 29988018] at several differentiation stages. The differentiations were performed in one biological replicate, wit...
ORGANISM(S): Homo sapiens 
2021-05-29 | E-MTAB-10488 | biostudies-arrayexpress
TranscriptomicsThe gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons
A challenge in systems biology is to understand the gene regulatory networks that connect early cellular specification to terminal differentiation of specific cell types. In neurogenesis, neural specification has been well studied, but the link between the proneural transcriptional regulators of spe...
ORGANISM(S): Drosophila melanogaster 
2011-02-18 | E-GEOD-21520 | biostudies-arrayexpress
GenomicsPacbio Hifi sequencing of a male cape dune mole-rat kidney sample
One PacBio Hifi sequencing run from the kidney of a single male CDMR (Bathyergus suillus) sample used to make the mBatSui1.1.primary genome assembly as an evolutionary comparator to our telomere-to-telomere naked mole-rat genome assembly. Specifically, we assembled a CDMR from a wild-derived sample ...
ORGANISM(S): Bathyergus suillus 
2026-08-05 | E-MTAB-17312 | biostudies-arrayexpress
TranscriptomicsHypoxia transcriptome sequencing of blind mole rat (BMR, Spalax galili) and rat (Rattus norvegicus)
Deep sequencing of mRNA from Spalax galili and Rattus norvegicus Total RNAs were isolated from the brain of female BMRs under various oxygen concentrations (3%, 6%, 10%, 14%, and 21%) for 6 hours. We also got RNAs from the brain of rats under 6%, 10%, 14%, and 21% oxygen conditions.
ORGANISM(S): Nannospalax galili 
2014-06-05 | E-GEOD-49485 | biostudies-arrayexpress
UnknownPrenatal case of Simpson-Golabi-Behmel syndrome with a de novo 370Kb-sized microdeletion of Xq26.2 compassing partial GPC3 gene and review.
Not available
S-EPMC8404223 | biostudies-literature
UnknownmTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
Not available
S-EPMC8141029 | biostudies-literature
UnknownA mitogenomic timetree for Darwin's enigmatic South American mammal Macrauchenia patachonica.
Not available
S-EPMC5490259 | biostudies-literature
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