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UnknownChurch attendance, allostatic load and mortality in middle aged adults.
Not available
S-EPMC5433740 | biostudies-literature
TranscriptomicsDynamic changes in gene expression in vivo predict prognosis of tamoxifen-treated patients with breast cancer
Tamoxifen is the most widely prescribed anti-estrogen treatment for patients with ER-positive breast cancer. However, there is still a need for biomarkers that reliably predict endocrine sensitivity in breast cancers and these may well be expressed in a dynamic manner. In this study we assessed ge...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22386 | biostudies-arrayexpress
TranscriptomicsAnalysis of the role of yeast Slf1p in translation of specific mRNAs during oxidative stress response
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Slf1p is an atypical La motif containing protein (LARP). LARPs are members of a superfamily of RNA-binding proteins conserved across eukaryotes. We performed transcriptomics and RIP-Seq analys...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-01 | E-MTAB-2567 | biostudies-arrayexpress
TranscriptomicsAnalysis of the role of yeast Sro9p in controlling the translation of specific mRNAs
The mechanisms by which RNA-binding proteins control the translation of subsets of mRNAs are not yet clear. Sro9p is an atypical La motif containing protein (LARP). LARPs are members of a superfamily of RNA-binding proteins conserved across eukaryotes. We performed transcriptomics and RIP-Seq analys...
ORGANISM(S): Saccharomyces cerevisiae 
2015-05-01 | E-MTAB-2568 | biostudies-arrayexpress
UnknownScalable microfluidics for single-cell RNA printing and sequencing.
Not available
S-EPMC4487847 | biostudies-literature
TranscriptomicsNext generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy
Early chemotherapy for advanced/metastatic non-castration resistant prostate cancer (PCa) may improve overall patient survival. We studied the safety, tolerability and early efficacy of up-front docetaxel chemotherapy and androgen deprivation therapy (ADT) versus ADT alone for patients with newly-d...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-51005 | biostudies-arrayexpress
UnknownPhysical Activity and Incident Hypertension in African Americans: The Jackson Heart Study.
Not available
S-EPMC5302780 | biostudies-literature
ProteomicsProteomics analysis of the effect of deletion of PUF3 on yeast via LC-MSMS.
The Puf family of RNA-binding proteins regulate the expression of genes by controlling protein synthesis or stimulating RNA decay. Puf3p is one of six Puf-family members in Saccharomyces cerevisiae. Puf3p has been characterised previously as regulating mRNA decay of nuclear mRNAs that encode for mi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-04-13 | PXD001903 | Pride
Lc-msms Yeast Label-free quantification 
TranscriptomicsThe Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth
Androgen ablation therapy (AAT) is standard treatment for locally-advanced/metastatic prostate cancer (PCa). Many patients develop castration-resistance (CRPCa) after ~2-3 years, with a poor prognosis. The molecular mechanisms underlying CRPCa progression are unclear. mRNA-Seq was performed on tu...
ORGANISM(S): Homo sapiens 
2013-10-07 | E-GEOD-48403 | biostudies-arrayexpress
ProteomicsIdentification of protein-protein interactions involving the eIF4E binding proteins Caf20p and Eap1p on yeast via affinity purification and LC-MSMS.
There are multiple translational control pathways. These include pathways involving eIF4E binding proteins (4E-BPs), which inhibit translation by binding and sequestering the 5’ cap binding protein eIF4E away from its partner eIF4G. Saccharomyces cerevisiae has two 4E-BPs: Caf20p and Eap1p. Previou...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-06-29 | PXD001407 | Pride
Lc-msms Affinity purification Yeast Label-free quantification 
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