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GenomicsDifferential methylation between mouse embyronic stem cell states
We generated RRBS data between Rex1-high and Rex1-low cells to identify differentially methylated promoters. We observe bimodal methylation levels in both subpopulations, and that Rex1-low cells accumulate increased levels of methylation, frequently as a function of local CpG density We sorted Rex1 ...
ORGANISM(S): Mus musculus 
2014-07-21 | E-GEOD-58396 | biostudies-arrayexpress
TranscriptomicsA high-resolution map of active promoters in the human genome
Our ability to understand the control logic embedded in the human genome is limited by a lack of accurate information of the promoter sequences for most genes. Promoters are a unique class of control sequences, serving as the binding sites for both sequence-specific factors and the general transcri...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-2672 | biostudies-arrayexpress
TranscriptomicsIgG control ChIP in HeLa cells
Control IgG ChIP vs matched total for HeLa cells. Three biological replicates. ChIP-chip of IgG; look for non-specific binding sites.
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4338 | biostudies-arrayexpress
TranscriptomicsPOLII localization in HeLa cells
RNA polymerase II (POLR2A; POLII) was localized via ChIP-chip using N20 Ab-mediated pull-down of POLII Classical design; ChIP-chip of POLII in ENCODE regions
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4337 | biostudies-arrayexpress
TranscriptomicsMYC binding sites in HeLa cells
MYC binding sites determined in HeLa cells using ChIP-chip ChIP-chip
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4354 | biostudies-arrayexpress
TranscriptomicsDistinct transcriptional outputs associated with mono- and di-methylated histone H3 arginine 2
Dimethylation of histone H3 arginine 2 (H3R2me2) maintains transcriptional silencing by inhibiting Set-1 mediated trimethylation of H3K4. Here we demonstrate that arginine 2 is also monomethylated (H3R2me1) in yeast but that its functional characteristics are distinct from H3R2me2: (a) H3R2me1 does ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-06 | E-GEOD-14453 | biostudies-arrayexpress
UnknownQualitative evaluation of a community health representative program on patient experiences in Navajo Nation.
Not available
S-EPMC6950858 | biostudies-literature
UnknownTarget engagement and immunogenicity of an active immunotherapeutic targeting pathological α-synuclein: a phase 1 placebo-controlled trial.
Not available
S-EPMC11405261 | biostudies-literature
TranscriptomicsDNaseI/Array GM06990
The goal of this study was to map DNaseI sensitivity and DNaseI hypersensitive sites over the ENCODE regions in human lymphoblastoid cells (GM06990, Coriell). DNA fragments released from DNaseI cut sites in nuclear chromatin were collected and hybridized to the Nimblegen ENCODE array. DNaseI-fragme...
ORGANISM(S): Homo sapiens 
2010-07-01 | E-GEOD-4334 | biostudies-arrayexpress
UnknownDetermining the Longitudinal Serologic Response to COVID-19 Vaccination in the Chronic Kidney Disease Population: A Clinical Research Protocol.
Not available
S-EPMC10028441 | biostudies-literature
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