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TranscriptomicsAlterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which has been shown to increase the susceptibility of various bacteria to antimicrobials and demonstrated to have broad antimicrobial activity. This study describes transcriptome alterations in S. aureus strain COL grown with diclofenac ...
ORGANISM(S): Staphylococcus aureus subsp. aureus COL 
2011-07-18 | E-GEOD-30724 | biostudies-arrayexpress
ProteomicsQuantitative Characterization of Clinically Relevant Drug-Metabolizing Enzymes and Transporters in Rat Liver and Intestinal Segments for Applications in PBPK Modeling
Rats are extensively used preclinical models for assessing drug pharmacokinetics (PK) and tissue distribution; however, a successful translation of the rat data requires information on the differences in drug metabolism and transport mechanisms between rats and humans. To partly fill this knowledge ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-02-05 | PXD039271 | Pride
Pbpk modeling Quantitative proteomics Drug metabolism Total protein approach Digoxin Drug transport Interspecies differences 
TranscriptomicsChromosome wide analysis of parental allele specific chromatin and DNA methylation along mouse distal chr7
Imprinted genes are monoallelically expressed according to parental inheritance. The maternally and paternally inherited alleles are distinguished epigenetically by DNA methylation and histone modifications. Chromosome-wide Chromatin immunoprecipitation (ChIP) and MIRA analysis of MatDup.dist7 and ...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-26891 | biostudies-arrayexpress
TranscriptomicsChromosome wide analysis of parental allele specific chromatin and DNA methylation along the central part of mouse chr7
Imprinted genes are monoallelically expressed according to parental inheritance. The maternally and paternally inherited alleles are distinguished epigenetically by DNA methylation and histone modifications. Chromosome-wide Chromatin immunoprecipitation (ChIP) and MIRA analysis of MatDup.dist7 and ...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-26892 | biostudies-arrayexpress
TranscriptomicsChromosome wide analysis of parental allele specific chromatin and DNA methylation along mouse distal chr15
Imprinted genes are monoallelically expressed according to parental inheritance. The maternally and paternally inherited alleles are distinguished epigenetically by DNA methylation and histone modifications. Chromosome-wide Chromatin immunoprecipitation (ChIP) and MIRA analysis of MatDup.dist7 and ...
ORGANISM(S): Mus musculus 
2011-03-31 | E-GEOD-26893 | biostudies-arrayexpress
ProteomicsCerebrospinal fluid biomarkers in Idiopathic Intracranial Hypertension: an exploratory SWATH proteomics analysis
The pathogenesis of idiopathic intracranial hypertension (IIH) is currently poorly understood. Speculations regarding the role of cerebrospinal fluid (CSF) protein biomarkers in understanding the pathomechanism of IIH needs to be studied using the high-throughput omics approaches.In this study we ha...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD027751 | Pride
Idiopathic intracranial hypertension (iih) Cerebrospinal fluid (csf) Proteomics Biomarkers 
UnknownImproving event prediction using general practitioner clinical judgement in a digital risk stratification model: a pilot study.
Not available
S-EPMC11654091 | biostudies-literature
UnknownHaemodynamic and hyperaemic effects of adenosine in patients with atrial fibrillation undergoing quantitative myocardial perfusion cardiovascular magnetic resonance.
Not available
S-EPMC11670251 | biostudies-literature
UnknownAssessment of stunned and viable myocardium using manganese-enhanced MRI.
Not available
S-EPMC8186753 | biostudies-literature
UnknownCholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer.
Not available
S-EPMC5792308 | biostudies-literature
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