Sort   by:  
 Page size 
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
MetabolomicsMetabolic Profiling of CSF from People Suffering from Sporadic and LRRK2 Parkinson's Disease: A Pilot Study
CSF from unique groups of Parkinson's disease (PD) patients was biochemically profiled to identify previously unreported metabolic pathways linked to PD pathogenesis, and novel biochemical biomarkers of the disease were characterized. Utilizing both 1H NMR and DI-LC-MS/MS we quantitatively profiled ...
2022-09-02 | MTBLS863 | MetaboLights
ProteomicsMechanistic insight into the role of enzyme mevalonate kinase by a natural fatty acid -mediated killing of Leishmania donovani
We evaluated the anti-leishmanial efficacy of different saturated medium-chain fatty acids (FAs, C8-C18) where FA containing C8 chain, caprylic acid (CA), was found to be most potent against Leishmania donovani, the causative agent for visceral leishmaniasis (VL). Different analogs of CA with C8 cha...
ORGANISM(S): Leishmania donovani BPK282A1 
2022-10-14 | PXD034560 | Pride
Proteomics Ergosterol depletion Mevalonate kinase Competitive inhibition Caprylic acid Visceral leishmaniasis 
UnknownSynthesis of imidazol-1-yl-acetic acid hydrochloride: a key intermediate for zoledronic acid.
Not available
S-EPMC2605618 | biostudies-literature
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
Unknown'Pee'BuSt Trial: A single-centre prospective randomized study comparing functional and anatomic outcomes after augmentation  urethroplasty with penile skin graft versus buccal mucosa graft for anterior urethral stricture disease.
Not available
S-EPMC8520101 | biostudies-literature
UnknownNear UV-Visible electronic absorption originating from charged amino acids in a monomeric protein.
Not available
S-EPMC5609530 | biostudies-literature
UnknownAnalysis of the topology of Vibrio cholerae NorM and identification of amino acid residues involved in norfloxacin resistance.
Not available
S-EPMC1635172 | biostudies-literature
UnknownComplex multifractal nature in Mycobacterium tuberculosis genome.
Not available
S-EPMC5404331 | biostudies-literature
UnknownIntercalated MOF nanocomposites: robust, fluorine-free and waterborne amphiphobic coatings.
Not available
S-EPMC11775646 | biostudies-literature
Sort   by:  
 Page size