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ProteomicsUltra-sensitive proteomics using second generation micro pillar array LC technology with Orbitrap Exploris™ 480 and FAIMS
In the light of the ongoing single-cell revolution, scientific disciplines are combining forces with the ultimate goal to retrieve as much relevant data as possible from trace amounts of biological material. For single cell proteomics, this implies optimizing the entire workflow from initial cell is...
ORGANISM(S): Homo sapiens (Human) 
2021-06-28 | PXD024017 | Pride
Micro pillar Low-input proteomics Single sell proteomics 
UnknownPhenotypes and cytokines of NK cells in triple-negative breast cancer resistant to checkpoint blockade immunotherapy.
Not available
S-EPMC11969778 | biostudies-literature
UnknownAptamer-based proteomics of serum and plasma in acquired aplastic anemia.
Not available
S-EPMC6748047 | biostudies-literature
UnknownProteomic analysis of serum small extracellular vesicles identifies diagnostic biomarkers for neuroblastoma.
Not available
S-EPMC11368728 | biostudies-literature
TranscriptomicsQuantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub
The aim of the dataset was to study on a genome-wide level the impact of Lat deficiency on gene expression in resting and activated CD4+ T cells Lat+ and Lat? CD4+ T cells were isolated from lymph nodes and spleen of Latfl-dtr Tmat-Cre mice using a Dynabeads untouched mouse CD4 cells kit (Life Techn...
ORGANISM(S): Mus musculus 
2014-03-02 | E-GEOD-49507 | biostudies-arrayexpress
ProteomicsRole of ATR in mitochondrial functions and metabolism
The PIKK superfamily member ATR is a key factor in DNA damage response (DDR) and is vital for the maintenance of genomic stability. DNA single strand breaks (SSBs) and replication stress activate ATR to phosphorylate a wide range of downstream substrates, which activates cell cycle checkpoint, senes...
ORGANISM(S): Mus musculus (Mouse) 
2021-05-05 | PXD013414 | Pride
Metabolism Atr Mitochondrial function 
UnknownDe Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.
Not available
S-EPMC6323609 | biostudies-literature
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