Single-cell-type proteomics

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Proteomics (1088)
Unknown (316)
Transcriptomics (174)
Genomics (79)
Metabolomics (38)
Other (32)
Multiomics (14)

Organisms

Homo sapiens (258)
Mus musculus (94)
Arabidopsis thaliana (16)
Rattus norvegicus (9)
Saccharomyces cerevisiae (7)
Staphylococcus aureus (6)
Sus scrofa (3)
Zea mays (3)
Geobacter sulfurreducens PCA (2)
Rhodospirillum rubrum (2)
Dictyostelium discoideum (2)
Geobacter sulfurreducens (2)
Oncorhynchus mykiss (2)
Burkholderia cenocepacia (2)
Agaricus bisporus (1)
Larimichthys crocea (1)
Bacteroides cellulosilyticus (1)
Burkholderia cenocepacia H111 (1)
Dorea longicatena DSM 13814 (1)
Streptomyces natalensis ATCC 27448 (1)
Peromyscus leucopus (1)
Phaseolus vulgaris (1)
Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 (1)
Colinus virginianus (1)
Macaca nemestrina (1)
Pyrococcus furiosus (1)
Bacillus thuringiensis (1)
Bacillus subtilis subsp. subtilis str. 168 (1)
Propionibacterium freudenreichii subsp. shermanii (1)
Brassica napus (1)

Organisms

Homo sapiens (33)
Mus musculus (21)
Mesocricetus auratus (1)
Macaca fascicularis (1)
Candida albicans (1)
Schizosaccharomyces pombe (1)
Cunninghamia lanceolata (1)
Caenorhabditis elegans (1)
Rattus norvegicus (1)

Repository

MassIVE (446)
pride (307)
biostudies-arrayexpress (170)
jPOST (133)
ENA (66)
iProX (63)
geo (47)
PanoramaPublic (41)
PeptideAtlas (39)
MetaboLights (37)
PAXDB (32)
GPMDB (23)
EGA (6)
GNPS (1)

Tissue

Cell culture (60)
Brain (26)
Epithelial cell (21)
T cell (13)
Liver (12)
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B cell (10)
Blood (10)
Lung (9)
Fibroblast (8)
Others (7)
Heart (7)
Stem cell (7)
Monocyte (7)
Plasma Non-glyco (6)
Skin (6)
HeLa cell (6)
Permanent cell line cell (6)
Microglial cell (5)
Keratinocyte (5)
Cell suspension culture (5)
Embryo (5)
Leaf (5)
Hepatocyte (5)
Mucosal invariant T cell (4)
Blood plasma (4)
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Neuron of cerebral cortex (3)
Skeletal muscle fiber (3)
Type II pneumocyte (3)

Disease

Not Available (23)
Disease free (10)
Breast cancer (8)
Alzheimer's disease (4)
Tuberculosis (4)
COVID-19 (3)
Wounds and Injuries (3)
Colon cancer (3)
Acute leukemia (3)
Nemaline myopathy (2)
Lung small cell carcinoma (2)
Non-small cell lung carcinoma (2)
Lung adenocarcinoma (2)
Prostate adenocarcinoma (2)
Lymphoma (2)
Cervix carcinoma (2)
Parkinson's disease (2)
Influenza (2)
Glioblastoma (2)
Type 2 diabetes mellitus (2)
Locally advanced rectal cancer (1)
Normal (1)
Acute lymphocytic leukemia (1)
Susceptibility to dengue virus (1)
Dengue shock syndrome (1)
Interstitial lung disease (1)
Dengue hemorrhagic fever (1)
Bone chondrosarcoma (1)
Fascioliasis (1)
Buruli ulcer disease (1)

Technology Type

Mass Spectrometry (307)
Shotgun proteomics (154)
Bottom-up proteomics (74)
Data-independent acquisition (45)
Data-dependent acquisition (32)
Mass spectrometry (29)
Affinity purification coupled with mass spectrometry proteomics (25)
SWATH MS (19)
Gel-based experiment (9)
Top-down proteomics (8)
Mass spectrometry assay (6)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
All-ion fragmentation (4)
SRM/MRM (4)
NMR spectroscopy (3)
DiaPASEF (3)
HDMSE (3)
Affinity proteomics (2)
Illumina HiSeq 2000 (1)
SomaScan affinity proteomics (1)
Metaproteomics (1)
Mass spectrometry imaging (1)
Immunopeptidomics (1)

Instrument Platform

Q Exactive (96)
Orbitrap Fusion Lumos (54)
Q Exactive Plus (44)
Orbitrap Fusion (36)
LTQ Orbitrap Velos (35)
Q Exactive HF (27)
LTQ Orbitrap (26)
Instrument (23)
LTQ Orbitrap Elite (22)
Q Exactive HF-X (20)
Orbitrap Eclipse (20)
Orbitrap Exploris 480 (18)
Illumina HiSeq 2500 (5)
NextSeq 500 (5)
Illumina NovaSeq 6000 (3)
Illumina HiSeq 2000 (3)
BD Rhapsody Sequence Analysis Pipeline (1)
Aurora Cytek Cs 5L (1)
BD Rhapsody (1)
GenePix 4000 (1)
Affymetrix Gene Atlas System (1)
Agilent 2100 Bioanalyzer (1)
Spectronic Helios Alpha UV-Vis spectrophotometer (1)
Illumina Genome Analyzer IIx (1)
Bioanalyser (1)
Illumina NovaSeq X (1)
Illumina HiSeq X (1)
GenePix 4000B (1)
NextSeq 550 (1)
Illumina HiSeq 4000 (1)

Publication Date

2025 (152)
2024 (134)
2023 (130)
2022 (127)
2021 (91)
2020 (86)
2026 (74)
2017 (66)
2019 (61)
2016 (56)
2018 (50)
2015 (48)
2013 (38)
2010 (27)
2012 (22)
2011 (22)
2014 (19)
2009 (16)
2008 (8)
2007 (5)
2005 (3)
2006 (3)
2003 (1)

UNIPROT ID/AC

DERM_MOUSE (6)
SUN2_MOUSE (6)
ANK2_MOUSE (6)
NOL3_MOUSE (6)
H10_MOUSE (6)
S27A1_MOUSE (6)
RL18A_MOUSE (6)
MSPD1_MOUSE (6)
UBIM_MOUSE (6)
PGRC2_MOUSE (6)
MPRI_MOUSE (6)
T3HPD_MOUSE (6)
PREB_MOUSE (6)
VAMP5_MOUSE (6)
STEA3_MOUSE (6)
RAB6A_MOUSE (6)
COX17_MOUSE (6)
CLPT1_MOUSE (6)
HMGN2_MOUSE (6)
ATPK_MOUSE (6)
CX6A2_MOUSE (6)
RL35A_MOUSE (6)
COFA1_MOUSE (6)
TIM21_MOUSE (6)
TNNT3_MOUSE (6)
TCOF_MOUSE (6)
SAFB1_MOUSE (6)
CO3A1_MOUSE (6)
MAVS_MOUSE (6)
LEMD2_MOUSE (6)

ENSEMBL ID

ENSG00000170477 (13)
ENSMUSG00000027651 (12)
ENSMUSP00000141097 (10)
ENSMUSG00000021039 (9)
ENSG00000147251 (9)
ENSMUSP00000111587 (6)
ENSMUSP00000106991 (6)
ENSMUSG00000090272 (6)
ENSMUSG00000098557 (5)
ENSG00000247315 (2)
ENSMUSP00000141542 (1)

CHEBI ID

CHEBI:28044 (11)
CHEBI:18012 (9)
CHEBI:30769 (9)
CHEBI:6650 (9)
CHEBI:27266 (9)
CHEBI:16708 (9)
CHEBI:15428 (8)
CHEBI:16449 (8)
CHEBI:15741 (8)
CHEBI:22660 (8)
CHEBI:28300 (8)
CHEBI:30915 (8)
CHEBI:24898 (8)
CHEBI:25017 (8)
CHEBI:18186 (8)
CHEBI:17568 (7)
CHEBI:16335 (7)
CHEBI:16750 (7)
CHEBI:17822 (7)
CHEBI:26986 (7)
CHEBI:16811 (7)
CHEBI:26271 (7)
CHEBI:18237 (7)
CHEBI:25094 (7)
CHEBI:16467 (6)
CHEBI:15891 (6)
CHEBI:17050 (6)
CHEBI:17596 (6)
CHEBI:16027 (6)
CHEBI:32816 (6)

Metabolite Name

Succinic acid (7)
Citric acid (7)
Phenylalanine (6)
Alanine (6)
Glutaric acid (6)
Inosine (6)
Uridine (6)
Leucine (5)
Fumaric acid (5)
Isoleucine (5)
Glycine (5)
3-phosphoglycerate (5)
Sarcosine (5)
Hexadecanedioic acid (5)
Dodecanoic acid (5)
Azelaic acid (5)
Uracil (5)
Adenosine (5)
Adenine (5)
Creatine (5)
Guanosine (5)
Cinnamic acid (4)
Valine (4)
2-Methylglutaric acid (4)
Taurodeoxycholic acid (4)
Pentadecanoic acid (4)
Pantothenic acid (4)
Stearic acid (4)
Sebacic acid (4)
Mesaconic acid (4)

First Public Date

2026 (19)
2025 (13)
2024 (8)
2023 (5)
2022 (5)
2021 (4)
2020 (4)
2014 (3)
2019 (1)
2017 (1)
2016 (1)
2015 (1)
2011 (1)

Classification

fungi (1)

Modification

Not available (2)
4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (85)
RNA-seq of coding RNA (35)
Proteomic profiling by array (26)
ChIP-seq (4)
RNA-seq of coding RNA from single cells (3)
Cell line - High-throughput sequencing (2)
Transcription profiling by RT-PCR (2)
Other (2)
RNA-seq of total RNA (2)
Transcription profiling by SAGE (1)
Cell line - Single-cell sequencing (1)
Animal - One-color microarray (1)
ChIP-chip by tiling array (1)
Cell line - One-color microarray (1)
Animal - High-throughput sequencing (1)
Proteomic profiling by mass spectrometer (1)
Genotyping by array (1)
Comparative genomic hybridization by array (1)

Release Date

2025 (89)
2024 (42)
2023 (39)
2021 (35)
2022 (33)
2010 (28)
2015 (27)
2016 (24)
2014 (22)
2020 (21)
2013 (21)
2019 (18)
2012 (18)
2011 (18)
2018 (10)
2009 (9)
2026 (8)
2008 (8)
2017 (6)
2007 (4)
2005 (4)
2003 (1)
2001 (1)

Lab affiliation

Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (7)
Proteomics of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany (5)
Cellular Proteomics, Helmholtz Centre for Infection Research, Braunschweig, Germany (4)
USDA-ARS (3)
Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town (2)
Department of Thoracic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650000, Yunnan, China. (2)
Div. Clinical Protein Science and Imaging, Dept. of Clinical Sciences and Dept. of Biomedical Engineering, Lund University, Sweden (2)
Department of Neurology, Yale School of Medicine, Yale University, new haven CT, USA (2)
Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (2)
CECAD Excellence Center, University of Cologne, Germany, D-50931 Center for Physiology and Pathophysiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Germany, D-50931 (2)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (2)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (2)
EDyP (2)
DZNE Munich, Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (2)
University of Edinburgh (2)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (2)
John van Geest Centre, Nottingham Trent University (1)
Kaiser lab Goethe University Frankfurt Institute of Pharmaceutical Chemistry Max-von-Laue Str. 7-9 60438 Frankfurt am Main Germany (1)
1. Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; 2. Proteomics and Singal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany (1)
Department of Biology, University of Florida, Gainesville, FL, USA Proteomics and Mass Spectrometry, Interdisciplinary Center for Biotechnology Research (ICBR), University of Florida, Gainesville, FL, USA (1)
Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. Erasmus MC Cancer Institute, The Netherlands. Oncode Institute, Utrecht, The Netherlands. (1)
1Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7FZ, UK (1)
Max Planck Institute of Psychiatry, Munich, Germany Biomedical Center, Molecular Biology, Ludwig-Maximilians-Universitat, Munich, Germany (1)
1. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria 2. Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria (1)
Newcastle University Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK (1)
School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW, 2650,Australia (1)
University of Warwick, Shool of Life Sciences and Proteomics Research Technology Platform. (1)
Professor, Department of Biology, Norwegian University of Science and Technology, N-7491, Trondheim, Norway (1)
Center for Network Systems Biology, Boston University (1)
Assistant Professor, Pediatrics-Heme/Onc and Bone Marrow Transplantation (1)

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Redox proteomics reveal a role for peroxiredoxinylation in stress protection.

The redox state of proteins is essential for their function and guarantees cell fitness. Peroxiredoxins protect cells against oxidative stress, maintain redox homeostasis, act as chaperones, and transmit hydrogen peroxide signals to redox regulators. Despite the profound structural and functional...

2025-07-17 | MTBLS11979 | MetaboLights

Proteomics and metabolomics analysis based on exosomes revealed the response mechanism of Alicyclobacillus acidoterrestris to acid stress

Bacteria secrete exosomes containing stress-related molecules such as proteins and nucleic acids, which facilitate adaptation to challenging environments. In order to elucidate the role of A. acidoterrestris exosomes in its acid stress response, this study combined proteomics and metabolomics to ...

2025-09-13 | MTBLS12995 | MetaboLights

Proteomics and metabolomics analysis based on exosomes revealed the response mechanism of Alicyclobacillus acidoterrestris to acid stress

2025-09-14 | MTBLS12996 | MetaboLights

Integrated Proteomics and Metabolomics Analyses Revealed Potential Phospholipid-Related Biomarkers in Rabbit Atherosclerotic Plaques

BACKGROUND AND AIMS: Atherosclerosis, characterized by dysfunction of lipid metabolism and chronic inflammation, is considered as a metabolic disorder as well as a major contributor to cardiovascular diseases. However, metabolic signatures of atherosclerosis have not been well ex...

2024-09-26 | MTBLS9737 | MetaboLights

Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea via TGR5-FAK-RhoA/Rock signaling revealed by integrated metabolomics and proteomics

Irinotecan (CPT-11) is widely used for colorectal cancer treatment, with delayed-onset diarrhea as its primary side effect. Xiao-Chai-Hu-Tang (XCHT) has been clinically observed to alleviate diarrhea, but its mechanisms remain unclear. This study aimed to explore the underlying regulatory mechani...

2025-09-03 | MTBLS12931 | MetaboLights

Single-cell-type Spatial Proteomics Unveils Precision Medicine Insights in Composite Small Lymphocytic and Classical Hodgkin Lymphoma

Deep Visual Proteomics (DVP) is an innovative technique that enables spatially resolved sing-cell-type proteome analysis. The coexistence of classical Hodgkin lymphoma (cHL) and small lymphocytic lymphoma (SLL) in a single patient presents a challenging scenario for clinical decision-making. In this...

ORGANISM(S): Homo sapiens (Human)

2024-10-29 | PXD051795 | Pride

Single-cell Transcriptomics Combined With Interstitial Fluid Proteomics Defines Cell Type-Specific Immune Regulation in Atopic Dermatitis

PRJNA643988 | ENA

A framework for performing single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology

Metabolic reprogramming in cancer and immune cells occurs to support their increasing energy needs in biological tissues. Here we propose Single Cell SPAtially resolved METabolic (scSpaMet) framework for joint protein-metabolite profiling of single immune and cancer cells in male human tissues by in...

ORGANISM(S): Homo sapiens (Human)

2023-10-02 | PXD045840 | Pride

Human lung Endometrium imc imaging Tumor

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications.

Not available

S-EPMC10849471 | biostudies-literature

Development of a laser capture microscope-based single-cell-type proteomics tool for studying proteomes of individual cell layers of plant roots.

Not available

S-EPMC4888759 | biostudies-literature

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