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ProteomicsWidespread multi-targeted therapy resistance via drug-induced secretome fucosylation
Cancer secretome is a reservoir for aberrant glycosylation. How therapies alter this post translational cancer hallmark and the consequences thereof remain elusive. Here we show that an elevated secretome fucosylation is a pan-cancer signature of both response and resistance to multiple targeted the...
ORGANISM(S): Homo sapiens (Human) 
2023-04-05 | PXD022240 | Pride
N-linked glycosylation Resistance Fucosylation Targeted therapy Secretome 
ProteomicsUltra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome
The oral cavity is home to one of the most diverse microbial community of the human body and a major entry portal for pathogens. Its homeostasis is maintained by saliva, which fulfills key functions including lubrication of food, predigesting and bacterial defense. Consequently, disruptions in saliv...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080862 | MassIVE
ProteomicsH.sapiens - Saliva, iBAQ (Grassletal,genomemed2016)
abundance based on iBAQ, Interaction consistency score: 13.6, Coverage: 27
ORGANISM(S): 9606 
2016-00-00 | 1356012761 | PAXDB
ProteomicsH.sapiens - Plasma, iBAQ (Grassletal,genomemed2016)
abundance based on iBAQ, Interaction consistency score: 2.7, Coverage: 1
ORGANISM(S): 9606 
2016-00-00 | 2304673249 | PAXDB
ProteomicsDirect identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
Although mutations may represent attractive targets for immunotherapy, direct identification of mutated peptide ligands isolated from human leukocyte antigens (HLA) on the surface of native tumor tissue has so far not been successful. Using advanced mass spectrometry (MS) analysis, we survey the mel...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-01-30 | MSV000080517 | MassIVE
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