Sort   by:  
 Page size 
TranscriptomicsThe genomic landscape of pediatric T-cell acute lymphoblastic leukemia reveals novel X-linked somatic mutations associated with apoptosis resistance.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-78786 | biostudies-arrayexpress
ProteomicsIdentification of ETV6 bound protein by affinity purification of ETV6-HA fusion protein in REH cells
To determine the protein partners of ETV6, we expressed ETV6 and HA-tagged ETV6 in Reh pre-B leukemic cells. Anti-HA magnetic beads were used for affinity purification of ETV6-HA (and ETV6 control) from the nuclear and cytoplasmic fraction. Following purification on-beads digest and LC-MS/MS experim...
ORGANISM(S): Homo sapiens (Human) 
2022-01-26 | PXD031001 | Pride
Leukemia All Etv6 
TranscriptomicsThe genomic landscape of pediatric T-cell acute lymphoblastic leukemia reveals novel X-linked somatic mutations associated with apoptosis resistance. [RNA-Seq]
Background. T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with a dismal prognosis. It represents 15% of pediatric ALL and has a threefold higher incidence among males. T-cell transformation is a multi-step process involving cooperating events leading to altere...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-78785 | biostudies-arrayexpress
TranscriptomicsIntegration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia
B-cell precursor acute lymphoblastic leukemia (pre-B ALL) is the most common pediatric cancer. Although the genetic origin of the disease remains unclear, epigenetic modifications including DNA methylation are suggested to contribute significantly to leukemogenesis. We assessed the DNA methylation s...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-38235 | biostudies-arrayexpress
Sort   by:  
 Page size