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TranscriptomicsAnalysis of HSF2 target genes using a global promoter ChIP-chip strategy on mouse wild-type testis
Mapping of in vivo targets for HSF2 by using mammalian tissue material in a global ChIP-chip promoter screen. Chromatin was isolated from three wild-type (WT) mouse testes, crosslinked and sonicated into fragments of 100-500 bp, and the quality of the DNA was controlled before the immunoprecipitatio...
ORGANISM(S): Mus musculus 
2008-08-05 | E-GEOD-9289 | biostudies-arrayexpress
TranscriptomicsHSF1 regulates transcription of sex-chromosomal multicopy genes during post-meiotic repression
Mapping of in vivo targets for HSF1 by using mammalian tissue material in a global ChIP-chip promoter screen. Chromatin was isolated from three wild-type (WT) mouse testes, crosslinked and sonicated into fragments of 100-500 bp, and the quality of the DNA was controlled before the immunoprecipitatio...
ORGANISM(S): Mus musculus 
2010-08-31 | E-GEOD-22492 | biostudies-arrayexpress
TranscriptomicsLong non-coding Satellite III RNAs link the heat shock response and cell proliferation
Genomes of complex organisms encode a wide variety of long non-coding RNAs (lncRNAs) that regulate gene expression. In human cells exposed to heat stress, transcription of lncRNAs is highly induced from Satellite III sequences located primarily within locus 9q12. Expression of Sat III transcripts is...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-58439 | biostudies-arrayexpress
ProteomicsLC-MS/MS from human cell lines PC3, HS578T, MDA-MB-231 and MCF10A
Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC/ESI-MS/MS) was used in the human cell lines HS578T, MDA-MB-231, MCF10A, and PC3. Label free quantification of protein abundances enabled comparison of the expression levels of talin 1 and talin 2 within each cell line. Mass s...
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD058465 | Pride
Human 231 Mda-mb Hs578t Pc3 Mcf10a 
GenomicsHeat shock-induced changes in chromatin binding of SUMO2/3 modified proteins
Heat shock induces rapid modification of proteins with SUMO2/3. This study concentrated in charaterizing how these changes are reflected on SUMOylation of chromatin bound proteins, trancsription, and chromatin binding of SUMO ligase PIAS1. Comparison of chromatin SUMO2/3 modification pattern in non-...
ORGANISM(S): Homo sapiens 
2015-07-02 | E-GEOD-66448 | biostudies-arrayexpress
TranscriptomicsHSF1 Is Required for Tumor Progression whereas HSF2 Suppresses Invasiveness of Prostate
Prostate cancer (PrCa) is one of the most common malignancies in Western countries. However, the pathways that promote invasion, especially in late-stage castration-resistant PrCa (CRPC), are poorly understood. Heat shock factors (HSFs) are transcriptional regulators essential for cell survival upon...
ORGANISM(S): Homo sapiens 
2013-12-23 | E-GEOD-48672 | biostudies-arrayexpress
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