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ProteomicsAn automated intact glycopeptide enrichment method for serum site-specific N-glycoproteomic analysis
We developed an automated glycopeptide enrichment method for the analysis of serum site-specific N-glycoproteome. This automated method allowed for processing one sample within 20 min. It showed higher enrichment specificity, more intact glycopeptide identifications, and better quantitative reproduc...
ORGANISM(S): Homo Sapiens (human) 
2021-04-06 | PXD025151 | JPOST Repository
MetabolomicsSerum Metabolomic Profiling Reveals Load-Specific Adaptations to Resistance Training
This study deposits the untargeted ¹H-NMR serum metabolomics dataset of a parallel-group, longitudinal resistance training intervention designed to identify load-specific and training-status-specific metabolomic signatures in healthy young men. Seventeen healthy young men (age 24 ± 3 yr; height 173 ...
2026-07-20 | MTBLS15091 | MetaboLights
ProteomicsSite-specific Extraction of O-linked glycopeptides (EXoO) Maps Landscape of In Vivo O-linked Glycoproteome
Protein glycosylation is one of the most common protein modifications and plays essential roles in biology and therapeutics. However, the analysis of in vivo O-linked glycosylation, a major type of protein glycosylation, has been severely impeded by the scarcity of technology. Here, a chemoenzymatic...
ORGANISM(S): Homo sapiens (Human) 
2018-12-05 | PXD009476 | Pride
Site-specific Glycosylation Exoo In vivo O-linked 
ProteomicsSite-specific incorporation of two noncanonical amino acids in GFP
Site-specific incorporation of two noncanonical amino acids for two-color bioorthogonal labeling and chemical-controlled crosslinking of proteins on live mammalian cells
ORGANISM(S): Mus Musculus (mouse) 
2020-06-11 | PXD019411 | JPOST Repository
MetabolomicsMonocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer’s disease-related traits in the murine brain

Bacteroides thetaiotaomicron (B. theta) dominates the gut microbiome of most mammals. This strictly anaerobic gut symbiont colonizes the mucus layer of host intestinal epithelial cells in both healthy and diseased conditions. Reduced neuronal and vagal afferent innervation observed in ge...

2025-12-15 | MTBLS12896 | MetaboLights
ProteomicsRelative Quantitative Analysis of Site-Specific N-Linked Glycosylation in Hyperglycosylated In-terferon-β via Mass Spectrometry
Glycosylation is a critical determinant of the efficacy, stability, and pharmacological behavior of therapeutic proteins. R27T, an engineered variant of interferon-β1a, contains two N-glycosylation sites (Asn25 and Asn80), increasing its structural complexity and analytical requirements. In this stu...
ORGANISM(S): Homo sapiens (Human) 
2026-09-21 | PXD077477 | Pride
Interferon beta  n-linked glycan  site-specific glycosylation  relative quantitative analysis  r27t 
TranscriptomicsSaccharomyces cerevisiae 3' poly(A) site mapping
The use of alternative polyadenylation sites is common and affects the post-transcriptional fate of mRNA, including its stability, localization, and translation. Here we present a method for genome-wide and strand-specific mapping of poly(A) sites and quantification of RNA levels at unprecedented ef...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-10 | E-GEOD-40110 | biostudies-arrayexpress
ProteomicsData files for site specific S-acylation
Raw data files for site specific S-acylation identification.
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) Homo Sapiens (ncbitaxon:9606) 
2023-05-31 | MSV000092063 | MassIVE
MetabolomicsCoupling Inflammatory Resolution to Osteogenesis: Lymphatic Vessels as Stage-specific Niche Regulators in Skeletal Healing

Skeletal healing requires the coordinated resolution of inflammation and precise lineage commitment of mesenchymal progenitors, yet the mechanisms coupling these processes remain incompletely defined. Here, we reveal that lymphatic vessels in bone serve as dynamic orchestrato...

2026-01-17 | MTBLS13645 | MetaboLights
ProteomicsSite-Specific Competitive Kinase Inhibitor Target Profiling Using Phosphonate Affinity Tags
Protein kinases are prime targets for drug development due to their involvement in various cancers. However, selective inhibition of kinases, while avoiding off-target effects remains a significant challenge for the development of protein kinase inhibitors. Activity-based protein profiling (ABPP), i...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058749 | Pride
Chemical proteomics  activity-based protein profiling  site-specific  protein kinase inhibitor profiling  ephrin receptor inhibitor  nvp-bhg712 
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