Sort   by:  
 Page size 
TranscriptomicsGene expression microarray of: 1) Cbx1 null versus revertant (single allele expression), and 2) Jarid2 null versus revertant, mutant mouse ES cells.
Gene expression as measured by microarray, in order to determine the cohort of differentially expressed genes, in each of two different mutant ES cell lines (Cbx1 and Jarid2), each comparing the respective null mutant ES cells to revertant (single allele expression) mutant ES cells. Hybridization wa...
ORGANISM(S): Mus musculus 
2017-09-12 | E-MTAB-5930 | biostudies-arrayexpress
TranscriptomicsTimecourse gene expression microarray analysis of bi-allelic targeted Setdb1 mutant mouse ES cells, comparing cells with one inducible conditional (floxed) null allele and a second constitutive null allele, to control mouse ES cell lines.
Gene expression microarray analysis of Setdb1 inducible conditional (floxed) mutant (Setdb1^tm1c(EUCOMM)Wtsi/Setdb1^tm1Wcs) compared to control (Setdb1^tm1c(EUCOMM)Wtsi/+) ES cell lines, without 4'OHT treatment, and timecourse samples following a 48 hour 4'OHT treatment. The 4'OHT induces Cre recom...
ORGANISM(S): Mus musculus 
2017-09-12 | E-MTAB-5931 | biostudies-arrayexpress
TranscriptomicsmiR-25 regulates Wwp2 and Fbxw7 and promotes reprogramming of mouse somatic cells
To reprogram mouse embryonic fibroblasts (MEFs) to induced Pluripotent Stem Cells (iPSCs), we constructed the PiggyBac (PB) transposon carrying the four Yamanaka factor cDNAs controlled by a CAG promoter (PB-CAG-OCKS, Oct4, cMyc, Klf4 and Sox2). As the baseline reprogramming control, we transfected ...
ORGANISM(S): Mus musculus 
2011-10-10 | E-MTAB-409 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of mouse embryonic stem cell lines with Dgcr8 mutations to investigate the broad role of miRNAs and individual miRNAs through the reintroduction of miRNA mimics
These experiments were conducted as part of a study to derive the targets of miRNAs. Two independent BayGenomics mouse embryonic stem cell lines (XH157 and XG058), each bearing a gene trap between exons 9 and 10 of the Dgcr8 locus (ENSMUST00000115633, Ensembl v53) were further mutagenised by the tar...
ORGANISM(S): Mus musculus 
2012-08-20 | E-MTAB-418 | biostudies-arrayexpress
UnknownDisease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium.
Not available
S-EPMC5546242 | biostudies-literature
UnknownImpact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Not available
S-EPMC11443006 | biostudies-literature
UnknownIdentification of genetic elements in metabolism by high-throughput mouse phenotyping.
Not available
S-EPMC5773596 | biostudies-literature
Sort   by:  
 Page size