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This SuperSeries is composed of the following subset Series: GSE25210: Genome-wide mapping of Flag-Evi1 in SKOV-3 ovarian carcinoma cells GSE25212: Effects of Evi1 knockdown and overexpression in SKOV-3 ovarian carcinoma cells GSE33724: Effects of EVI1 mild expression in HeLa cells Refer to individu...
ORGANISM(S): Homo sapiens 
Kallikrein-related peptidase 7 (KLK7) is a serine peptidase that is over-produced in the most lethal form of ovarian cancer, called high grade serous ovarian cancer (HGSOC). To determine its underlying molecular mechanism of action, a comprehensive analysis of KLK7 degradome in the SKOV-3 cell-secre...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD003752 | Pride
Discovery of Evi1Δ324 genomic occupancy and target genes ChIP-enriched DNA and input DNA were analyzed by Solexa sequencing.
ORGANISM(S): Homo sapiens 
Subinhibitory concentrations of the neuroleptic drug thioridazine (TDZ) are well-known to enhance the killing of methicillin-resistant S. aureus (MRSA) by β-lactam antibiotics, however, the mechanism underlying the synergy between TDZ and β-lactams is not fully understood. In the present study we ...
ORGANISM(S): Staphylococcus aureus subsp. aureus USA300_FPR3757 
ATAC-seq was performed in the ovarian cancer cell lines COV-434, ES-2, Kuramochi, OAW28, OAW42, OVISE, SKOV-3, TOV-112D. The aim of this experiment was to detect open chromatin sites. Enhancers are associated with open chromatin sites flanked by histones with H3K4me1 and H3K27ac marks. Therefore, th...
ORGANISM(S): Homo sapiens 
Kallikrein-related peptidase 7 (KLK7) is a serine peptidase that is over-produced in the most lethal form of ovarian cancer, called high grade serous ovarian cancer (HGSOC). To determine its underlying molecular mechanism of action, a comprehensive analysis of KLK7 degradome in the SKOV-3 cell-secre...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD003812 | Pride
Discovery of Evi1 genomic occupancy and target genes ChIP-enriched DNA and input DNA were analyzed by Solexa sequencing.
ORGANISM(S): Homo sapiens 
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