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TranscriptomicsAffymetrix GeneChip® human gene 2.0 ST array analysis of SKOV-3 human ovarian cancer cells following siRNA knockdown of MAD2 or TLR4 compared to cells transfected with scrambled negative control siRNAs.
Both TLR4 and MAD2 are biomarkers associated with paclitaxel resistance in ovarian cancer. Therefore we performed microarray analysis following knockdown of each marker in SKOV-3 cells to gain greater insight into key downstream pathways that these biomarkers activate and also determine any potenti...
ORGANISM(S): Homo sapiens 
2020-12-06 | E-MTAB-8440 | biostudies-arrayexpress
TranscriptomicsSKOV-3TR
Human paclitaxel-resistant (SKOV-3TR) ovarian cancer cell line and the parent SKOV-3 cell line were grown in RPMI medium containing 10% fetal calf serum. The experiment was done to compare the expression differences between the parent SKOV-3 cell line and the derived SKOV-3TR cell line. Cells were ...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-2627 | biostudies-arrayexpress
TranscriptomicsComparisons of the global gene profile between C-CPE treated- and untreated- SKOV-3 ovarian cancer cells.
A microarray analysis was performed to compare the global gene expression profile between C-CPE treated- and untreated- SKOV-3 ovarian cancer cells. SKOV-3 cells were treated with or without C-CPE for 72 hours, and total RNA was extracted and microarray was perfomed to compare the gene profiling cha...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-22421 | biostudies-arrayexpress
TranscriptomicsMicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis
Background: Psoriasis is a systemic inflammatory skin disease. MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that recently have been found in the blood to be relevant as disease biomarkers. Objective: We aimed to explore miRNAs potential as blood biomarkers for psoriasis. Methods:...
ORGANISM(S): Homo sapiens 
2014-06-10 | E-GEOD-55515 | biostudies-arrayexpress
UnknownP-MAPA and Interleukin-12 Reduce Cell Migration/Invasion and Attenuate the Toll-Like Receptor-Mediated Inflammatory Response in Ovarian Cancer SKOV-3 Cells: A Preliminary Study.
Not available
S-EPMC6982916 | biostudies-literature
GenomicsEVI1 and AP1 Interact to Transcriptionally Regulate a Feed-Forward Loop Important for Cancer Cell Proliferation and Adhesion
This SuperSeries is composed of the following subset Series: GSE25210: Genome-wide mapping of Flag-Evi1 in SKOV-3 ovarian carcinoma cells GSE25212: Effects of Evi1 knockdown and overexpression in SKOV-3 ovarian carcinoma cells GSE33724: Effects of EVI1 mild expression in HeLa cells Refer to individu...
ORGANISM(S): Homo sapiens 
2012-01-15 | E-GEOD-25213 | biostudies-arrayexpress
UnknownProtective Effects of Nettle Tea on SKOV-3 Ovarian Cancer Cells Through ROS Production, Apoptosis Induction, and Motility Inhibition Without Altering Autophagy.
Not available
S-EPMC11507475 | biostudies-literature
TranscriptomicsTranscriptome analysis on ovarian cancer
We are studying signaling pathways and growth properties of cultured human ovarian cancer cells that are expressing the G protein-coupled receptor, luteinizing hormone receptor (LHR),particularly interested in the changes that occur when the receptor is activated by its cognate ligand, gonadotropin ...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-GEOD-27328 | biostudies-arrayexpress
TranscriptomicsComparisons of the global gene profile between CLDN4-overexpressing and CLDN4-silencing ovarian cancer cells.
A microarray analysis was performed to compare the global gene expression profile between CLDN4-overexpressing (Control) and CLDN4-silencing SKOV-3 ovarian cancer cells. CLDN4 gene was knocked down by CLDN4 siRNA lentivirus. Total RNA was extracted and microarray was perfomed to compare the gene pro...
ORGANISM(S): Homo sapiens 
2010-12-15 | E-GEOD-22493 | biostudies-arrayexpress
UnknownCytotoxic Activity of Novel GnRH Analogs Conjugated with Mitoxantrone in Ovarian Cancer Cells.
Not available
S-EPMC11397358 | biostudies-literature
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