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TranscriptomicsRegulation of Lifespan, Metabolism, and Stress Responses by the Drosophila SH2B Protein, Lnk
Drosophila Lnk is the single ancestral orthologue of a highly conserved family of structurally-related intracellular adaptor proteins, the SH2B proteins. As adaptors, they lack catalytic activity but contain several protein-protein interaction domains, thus playing a critical role in signal transduc...
ORGANISM(S): Drosophila melanogaster 
2016-03-30 | E-MTAB-4612 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Drosophila exposed to trametinib under normal and high sugar dietary conditions
The transcriptional response to the small molecule MEK inhbitor, trametinib, was analysed from RNA extracts prepared from 10-day old adult female Drosophila that had been maintained under normal and high sugar dietary conditions post-eclosion.
ORGANISM(S): Drosophila melanogaster 
2026-09-03 | E-MTAB-17017 | biostudies-arrayexpress
TranscriptomicsRNA-seq of dmGluRA[112b] mutant Drosophila against controls
The transcriptional response in 10-day old adult female flies homozygous for the dmGluRA[112b] mutation was compared to age-matched controls.
ORGANISM(S): Drosophila melanogaster 
2023-09-01 | E-MTAB-8307 | biostudies-arrayexpress
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