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ProteomicsInteraction proteomics of the human solute carrier (SLC) transporter superfamily
Solute carrier (SLC) transporters form a major superfamily which transport a wide range of substrates across cellular and organellar membranes. The superfamily consists of about 450 members and includes passive transporters, antiporters and symporters. To ensure the homeostatic regulation of metabol...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD055605 | Pride
Ppi resource Human slc Ap-ms Large-scale ap-ms 
ProteomicsQuantitative proteome profiling in HEK293 to validate RNAi targets
The solute carrier (SLC) transporter superfamily are important coordinators of metabolic and cellular homeostasis. Despite their importance for cellular homeostasis, SLCs remain a largely understudied group of proteins regarding their protein interactome. Thus, we conducted a largescale interactome ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD055192 | Pride
Dia Slc interactors Validation of sirnas Full proteome 
UnknownA Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome.
Not available
S-EPMC7552919 | biostudies-literature
ProteomicsInteraction proteomics of wildtype SLC16A6 (MCT7) and phospho-variants
The solute carrier (SLC) transporter superfamily are important coordinators of metabolic and cellular homeostasis. Despite their importance for cellular homeostasis, SLCs remain a largely understudied group of proteins regarding their protein interactome. Thus, we conducted a largescale interactome ...
ORGANISM(S): Homo sapiens (Human) 
2025-03-03 | PXD055141 | Pride
Phosphodegron Slc16a6 phsopho-variants Ap-ms 
UnknownThe solute carrier superfamily interactome.
Not available
S-EPMC12130317 | biostudies-literature
UnknownThe solute carrier superfamily interactome
Not available
S-SCDT-10_1038-S44320-025-00109-1 | biostudies-other
ProteomicsSLC15A4 (PHT1) interaction proteomics
Human genetics and mouse models provide compelling evidence for the involvement of SLC15A4 in endosomal TLR activation. To gain an understanding of the molecular mechanism, we set out to identify its binding partners by interaction proteomics. TAP-MS/MS analysis of different SLC15A4 protein variants...
ORGANISM(S): Homo sapiens (Human) 
2020-05-14 | PXD014254 | Pride
Human Slc Tap Cxorf21 Lc-ms/ms 
ProteomicsProtein binder based IP-MS of SLC12A6 (KCC3) in Hek293WT OE cell lines
Specific protein binders with high affinity, such as antibodies or nanobodies, are scarce for most solute carrier (SLCs) transporters. Moreover, general approaches that can systematically generate binders for multi-transmembrane proteins, such as SLCs, channels or GPCRs, are still missing. Purifying...
ORGANISM(S): Homo sapiens (Human) 
2024-06-17 | PXD046995 | Pride
Human Ip-ms Slc12a6 (kcc3) Protein binders 
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