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UnknownCharacterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis.
Not available
S-EPMC6816314 | biostudies-literature
UnknownInterferon inducible X-linked gene CXorf21 may contribute to sexual dimorphism in Systemic Lupus Erythematosus.
Not available
S-EPMC6520347 | biostudies-literature
ProteomicsSLC15A4 (PHT1) interaction proteomics
Human genetics and mouse models provide compelling evidence for the involvement of SLC15A4 in endosomal TLR activation. To gain an understanding of the molecular mechanism, we set out to identify its binding partners by interaction proteomics. TAP-MS/MS analysis of different SLC15A4 protein variants...
ORGANISM(S): Homo sapiens (Human) 
2020-05-14 | PXD014254 | Pride
Human Slc Tap Cxorf21 Lc-ms/ms 
UnknownRecapitulation of Candidate Systemic Lupus Erythematosus-Associated Variants in Koreans.
Not available
S-EPMC5056901 | biostudies-literature
UnknownTASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Not available
S-EPMC7610944 | biostudies-literature
TranscriptomicsTASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
Toll-like receptors (TLRs) have a crucial role in the recognition of pathogens and initiation of immune responses. Here we show that a previously uncharacterized protein encoded by CXorf21—a gene that is associated with systemic lupus erythematosus—interacts with the endolysosomal transporter SLC15A...
ORGANISM(S): Homo sapiens 
2020-05-13 | GSE133317 | GEO
UnknownDysregulation of X-linked gene expression in Klinefelter's syndrome and association with verbal cognition.
Not available
S-EPMC2094046 | biostudies-literature
GenomicsTASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
PRJNA551037 | ENA
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