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TranscriptomicsGermination of Leafy Spurge (Euphorbia esula) Seeds under Constant and Alternating Temperature
Transcriptome changes were investigated for Euphorbia esula (leafy spurge) seeds with a focus on the effect of constant and diurnal fluctuating temperature on dormancy and germination. Leafy spurge seeds do not germinate when incubated for 21 days at 20°C constant temperatures, but nearly 30% germin...
ORGANISM(S): Euphorbia esula 
2010-06-01 | E-GEOD-18533 | biostudies-arrayexpress
TranscriptomicsExpression data from TOP-GFP sorted colon cancer cells
Colon cancers typically contain tumor cell populations with differential WNT signaling activity. Colon cancer cells with high WNT-activity have been attributed increase tumorigenic potential and stem cell characteristics. We extracted tumor cells with differential WNT activity using fluorescent repo...
ORGANISM(S): Homo sapiens 
2012-02-16 | E-GEOD-32408 | biostudies-arrayexpress
TranscriptomicsTranscription Factor Promyelocytic Leukemia Zinc Finger Protein regulates Interferon Stimulated Gene expression
This SuperSeries is composed of the following subset Series: GSE15193: IFN-alpha Stimulated Gene Expression in Sensitive and Resistant Renal Cell Carcinoma Cell Lines GSE16196: Differential IFNa-stimulated gene expression profiles in PLZF-inducible U937T monocyte cells Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-16197 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human serum-free fibrocytes, serum-containing fibrocytes, CD14++CD16- Monocytes, CD14++CD16+ Monocytes, CD14+CD16++ Monocytes and macrophages
Serum-free Fibrocytes, Serum-containing Fibrocytes, CD14++CD16- Monocytes, CD14++CD16+ Monocytes, CD14+CD16++ Monocytes, Macrophages were all generated from up to 3 biological replicates from each of 3 separate donors. RNA was extracted (Ambion RNAqueous), labelled with cy3, mixed with cy5 labelled ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-MEXP-2811 | biostudies-arrayexpress
TranscriptomicsM12-28: MRX34 Biomarker study in animals bearing HuH7 orthotopic liver tumors [Affymetrix]
To identify direct tumor mRNA targets of miR-34a, tumor RNAs isolated from whole tumors from animals treated with negative control and MRX34 HuH7 cells were surgically implanted into the livers of Nod/Scid mice and allow to grow for multiple weeks. Once serum AFP levels reached levels consistent wi...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-58800 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD4 regulatory T cells that express either CD45RA or CD45RO
CD4 T cells taken from 6 donors were sorted into CD25hi CD45RA+ (na�ve Treg), CD25hi CD45RO+ (memory Treg), CD25- CD45RA+ (na�ve responder) and CD25- CD45RO+ (memory responder) populations.

RNA was extracted (Ambion RNAqueous), amplified (SMART), labelled with cy3, mixed with cy5 labelle...
ORGANISM(S): Homo sapiens 
2009-10-05 | E-MEXP-2372 | biostudies-arrayexpress
TranscriptomicsM12-8: MRX34 Biomarker study in animals bearing Hep3B orthotopic liver tumors [Illumina]
To identify direct tumor mRNA targets of miR-34a, tumor RNAs isolated from whole tumors from animals treated with negative control and MRX34 Hep3B cells were surgically implanted into the livers of Nod/Scid mice and allow to grow for multiple weeks. Once serum AFP levels reached levels consistent w...
ORGANISM(S): Homo sapiens 
2014-11-05 | E-GEOD-58892 | biostudies-arrayexpress
TranscriptomicsInhibition of the mitochondrial TCA cycle by monofluoroacetate in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29268 | biostudies-arrayexpress
TranscriptomicsIFN-alpha Stimulated Gene Expression in Sensitive and Resistant Renal Cell Carcinoma Cell Lines
The antiproliferative, antiviral, and immunomodulatory properties of interferons (IFNs) have led to its therapeutic implementation. IFNs effects are mediated by a complex network of signal transducers, culminating in IFN-stimulated gene (ISG) induction. This complexity leads to diverse clinical resp...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15193 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human distinct types of fibrocyte differentiate in the presence and abscence of serum
Fibroblasts, Serum-free Fibrocytes, Serum-containing Fibrocytes, Monocytes, Macrophages, Osteoclasts, immature Dendritic Cells, and mature Dendritic Cells were all generated from 3 biological replicates from each of 3 separate donors. RNA was extracted (Ambion RNAqueous), labelled with cy3, mixed w...
ORGANISM(S): Homo sapiens 
2010-04-29 | E-MEXP-2434 | biostudies-arrayexpress
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