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MetabolomicsRegional Immunological and Microbial Characterization of Peyer's Patches in the Small Intestine of Bactrian Camels

Background: Our earlier research showed that Bactrian camels have a unique lymph aggregation structure that is similar to ileal Peyer's patches (PPs) and plays a role in the mucosal immunology of the digestive tract. However, Bactrian camels exhibit PPs not only in the ileum but also in all segme...

2024-11-11 | MTBLS10376 | MetaboLights
MetabolomicsInhibition of diamine oxidase promotes uptake of putrescine from rat small intestine
Not available
ORGANISM(S): Rattus norvegicus 
ST000401 | MetabolomicsWorkbench
ProteomicsConstruction of small intestine-like tissue by reproducing interstitial flow on-chip
Significant progress has been recently achieved in generating in vitro human small intestine models. Nonetheless, there remains ample opportunity for enhancement, both in terms of structure and function, within the current model. In this study, our objective is to construct a multilayered small inte...
ORGANISM(S): Homo Sapiens (human) 
2024-11-16 | PXD047318 | JPOST Repository
MetabolomicsBile acid targeted metabolomics of the small intestine in malnourished and control mice
Not available
ORGANISM(S): Mus musculus 
ST000222 | MetabolomicsWorkbench
MetabolomicsMetabolic network construction reveals probiotic-specific colonization resistance in a synthetic small intestinal community

The gut microbiota is essential to host health. Probiotics can be used as a microbiota targeted therapy to improve host health. However, probiotic molecular mechanisms of action and probiotics targeting the small intestinal microbiota are often not elucidated. In this study, we construct a three ...

2024-09-26 | MTBLS7370 | MetaboLights
MetabolomicsMetabolites in contents of small intestine in wild type and DAOG181R/G181R mice
Not available
ORGANISM(S): Mus musculus 
ST001439 | MetabolomicsWorkbench
MetabolomicsSmall intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
Small intestinal bacterial overgrowth (SIBO) has been implicated in symptoms associated with functional gastrointestinal disorders (FGIDs), though mechanisms remain poorly defined and treatment involves non-specific antibiotics. Here we show that SIBO based on duodenal aspirate culture reflects an o...
2019-04-30 | MTBLS876 | MetaboLights
MetabolomicsUntargeted metabolomic analysis in cats with naturally occurring inflammatory bowel disease and alimentary small cell lymphoma
Feline chronic enteropathy (CE) is a common gastrointestinal disorder in cats and mainly comprises inflammatory bowel disease (IBD) and small cell lymphoma (SCL). Differentiation between IBD and SCL can be diagnostically challenging. We characterized the fecal metabolome of 14 healthy cats and 22 ca...
2021-07-13 | MTBLS440 | MetaboLights
TranscriptomicsSexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice
There is increasing appreciation for sexually dimorphic effects, but the molecular mechanisms underlying these effects are only partially understood. In the present study, we explored transcriptomics and epigenetic differences in the small intestine and colon of prepubescent male and female mice. In...
ORGANISM(S): Mus musculus 
2015-09-02 | E-GEOD-57516 | biostudies-arrayexpress
TranscriptomicsStructural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice [Small Intestine data]
By regulating digestion and absorption of nutrients and providing a barrier against the external environment the intestine provides a crucial contribution to the maintenance of health. To what extent aging-related changes in the intestinal system contribute to the impaired health of the aging body i...
ORGANISM(S): Mus musculus 
2012-09-03 | E-GEOD-39974 | biostudies-arrayexpress
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