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UnknownThe annotation of both human and mouse kinomes in UniProtKB/Swiss-Prot: one small step in manual annotation, one giant leap for full comprehension of genomes.
Not available
S-EPMC2500232 | biostudies-literature
Transcriptomicsmature piRNAs expression profile in human bronchial epithelial (HBE) and non-small cell lung cancer (NSCLC) cells
To elucidate potential roles of piRNA in lung cancer, we analyzed global piRNA expression profiles in 8 NSCLC and 3 HBE cell lines. RNA-seq results showed that >99% of the approximately 4.5 million reads were between 26 and 32 bases. Most of the piRNA loci are represented by two or more identical re...
ORGANISM(S): Homo sapiens 
2016-06-27 | E-GEOD-57681 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of entire small intestines of control and CFTR null mice congenic on the C57Bl6 background to study the inflammation of cystic fibrosis mouse small intestine.
Total RNA was prepared from the entire small intestines of 40 day old Control and CFTR null mice (2 males and 1 female of each genotype), congenic on the black6 background, using TRIzol reagent. Mice were fed Peptamen from age 10 days to prevent intestinal obstruction.
ORGANISM(S): Mus musculus 
2007-12-15 | E-GEOD-765 | biostudies-arrayexpress
UnknownDiverse Taxonomies for Diverse Chemistries: Enhanced Representation of Natural Product Metabolism in UniProtKB.
Not available
S-EPMC7827101 | biostudies-literature
ProteomicsRescue of Escherichia coli auxotrophy by de novo small proteins
Increasing numbers of small proteins with diverse physiological roles are being identified and characterized in both prokaryotic and eukaryotic systems, but the origins and evolution of these proteins remain unclear. Recent genomic sequence analyses in several organisms suggest that new functions en...
ORGANISM(S): Escherichia coli 
2023-03-31 | PXD040161 | Pride
Escherichia coli Rna-binding De novo gene evolution Gene regulation His operon Auxotroph Small proteins 
ProteomicsComprehensive Identification of Soybean Long Non-coding RNAs Reveals a Subset of Small Peptide-Coding Transcripts
Long non-coding RNAs (lncRNAs) are defined as non-protein-coding transcripts that are at least 200 nucleotides long. They are known to play pivotal roles in regulating gene expression, especially during stress responses in plants. We used a large collection of in-house transcriptome data from variou...
ORGANISM(S): Glycine max 
2020-01-09 | PXD014553 | Pride
Long non-coding rna Proteomics Soybean Small peptide Transcriptomics 
ProteomicsProteome of silenced minichromosome maintenance protein 2 with siRNA on non-small cell lung cancer H1299 cells
Lung cancer is the leading cause of cancer-related mortality. The two main lung cancer types are small cell lung cancer (SCLC) and non-SCLC (NSCLC), where NSCLC comprises about 80-85% of all lung cancer. Despite the introduction of improved treatments, the overall survival rate of lung cancer patien...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD003743 | Pride
Non small cell lung cancer h1299 cells Rna interference Proteome Minichromosome maintenance protein 2 Itraq Lc-ms/ms 
ProteomicsComparative proteome analysis across non-small cell lung cancer cell lines
Non-small cell lung cancer (NSCLC) cell lines are widely used model systems to study molecular aspects of lung cancer. Comparative and in-depth proteome expression data across many NSCLC cell lines has not been generated yet, but would be of utility for the investigation of candidate targets and mar...
ORGANISM(S): Homo sapiens (Human) 
2015-09-14 | PXD002556 | Pride
Pca Non-small cell lung cancer K-ras Silac Proteome profiling Egfr 
Proteomicsproteomics of small extracellular vesicles (sEVs) from adipose tissue derived mesenchymal stem cells (AD-MSCs) stimulated with or without IFN-γ
Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) pre-conditioned MSCs (γ-sEVs). to anlyze the proteins in sEVs,...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD024647 | Pride
Small extracellular vesicle Mesenchymal stem cells 
UnknownMachine learning and bioinformatics-based insights into the potential targets of saponins in Paris polyphylla smith against non-small cell lung cancer.
Not available
S-EPMC9649596 | biostudies-literature
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