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ProteomicsPhosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange
Maintaining the dynamic structure of chromatin is critical for regulating the cellular processes that require access to the DNA template, such as DNA damage repair, transcription, and replication. Histone chaperones and ATP-dependent chromatin remodeling factors facilitate transitions in chromatin s...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055413 | Pride
Nucleosome Nucleosome assembly Chromatin remodeling Histone exchange Atp hydrolysis Histone chaperone Smarcad1 Phosphorylation Post-translational modification (ptm) 
ProteomicsPhosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange
Maintaining the dynamic structure of chromatin is critical for regulating the cellular processes that require access to the DNA template, such as DNA damage repair, transcription, and replication. Histone chaperones and ATP-dependent chromatin remodeling factors facilitate transitions in chromatin s...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055414 | Pride
Nucleosome Nucleosome assembly Chromatin remodeling Histone exchange Atp hydrolysis Histone chaperone Smarcad1 Phosphorylation Post-translational modification (ptm) 
ProteomicsPhosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange
Maintaining the dynamic structure of chromatin is critical for regulating the cellular processes that require access to the DNA template, such as DNA damage repair, transcription, and replication. Histone chaperones and ATP-dependent chromatin remodeling factors facilitate transitions in chromatin s...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055412 | Pride
Nucleosome Nucleosome assembly Chromatin remodeling Histone exchange Atp hydrolysis Histone chaperone Smarcad1 Phosphorylation Post-translational modification (ptm) 
ProteomicsPhosphorylation regulates the chromatin remodeler SMARCAD1 in nucleosome binding, ATP hydrolysis, and histone exchange
Maintaining the dynamic structure of chromatin is critical for regulating the cellular processes that require access to the DNA template, such as DNA damage repair, transcription, and replication. Histone chaperones and ATP-dependent chromatin remodeling factors facilitate transitions in chromatin s...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055450 | Pride
Nucleosome Nucleosome assembly Chromatin remodeling Histone exchange Atp hydrolysis Histone chaperone Smarcad1 Phosphorylation Post-translational modification (ptm) 
GenomicsHigh-throughput sequence data of ChIP performed with anti-SMARCAD1 (ASNA) or anti-CBP actibodies.
Histone acetylation and nucleosome remodeling play a pivotal role in transcriptional regulation. While histone acetylase and ATP-dependent chromatin remodeling activities have been well characterized, how the two activities are coordinated remains to be uncovered. We discovered ATP-dependent histone...
ORGANISM(S): Drosophila melanogaster 
2016-03-17 | E-GEOD-72666 | biostudies-arrayexpress
GenomicsChIP-Seq of SMARCAD1 and KAP1 in male mouse embryonic stem cells (E14)
The ATP dependent chromatin remodeler SMARCAD1 and the co-repressor KAP1 (Trim28/Tif1 beta) interact directly. We wanted to understand the interplay between these two proteins in the context of chromatin; in particular at repetitive sequences. Therefore, we carried out an investigation in E14 ES cel...
ORGANISM(S): Mus musculus 
2019-02-17 | E-MTAB-7011 | biostudies-arrayexpress
GenomicsChIP-Seq of chromatin remodeler SMARCAD1 and H3K9me3 in female mouse embryonic stem cells (PGK12.1 XX)
Investigation of the co-occurance of the ATP-dependent chromatin remodeler SMARCAD1 and the histone modification H3K9me3 in the genome of PGK12.1 XX ES cells. ChIP-seq of endogenous SMARCAD1 was carried out in control and SMARCAD1-knockdown ES cells using a double crosslinking procedure. Additionall...
ORGANISM(S): Mus musculus 
2019-02-17 | E-MTAB-7012 | biostudies-arrayexpress
GenomicsChIP-seq of FLAG-tagged SMARCAD1 in female mouse embryonic stem cells (PGK12.1 XX)
To understand the role of the SWI/SNF-like ATP-dependent chromatin remodeller SMARCAD1 in pluripotent murine embryonic stem (ES) cells we determined the genome wide binding of triple FLAG tagged SMARCAD1 in PGK12.1 XX ES cells. ChIP was carried out using an antibody against the FLAG-epitope (F1804, ...
ORGANISM(S): Mus musculus 
2019-02-17 | E-MTAB-7014 | biostudies-arrayexpress
GenomicsLoss of SMARCAD1 mitigates tauopathy
Loss of SMARCAD1 mitigates tauopathy
PRJNA1263027 | ENA
GenomicsSMARCAD1 Regulates Nucleosome Positioning and Maintenance of the Naïve Pluripotent State
SMARCAD1 Regulates Nucleosome Positioning and Maintenance of the Naïve Pluripotent State
PRJNA208009 | ENA
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