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TranscriptomicsTranscription profiling by array of cancer associated fibroblasts from pancreatic ductal adenocarcinoma in comparison to normal dermal fibroblasts
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor type with extremely high mortality (up to 92%) during 5 years after diagnosis. Here, cancer associated fibroblasts (CAF) from PDAC were compared to CAF from melanoma metastases (MELF) and to normal dermal fibroblasts (DF). The analysis w...
ORGANISM(S): Homo sapiens 
2021-11-01 | E-MTAB-8764 | biostudies-arrayexpress
TranscriptomicsFibroblasts prepared from stroma of basal cell carcinoma in comparison to normal dermal fibroblasts
Adult tissue stem cells are known to participate in cancer formation. Indeed, cells exhibiting markers of embryonic stem cells such as Oct-4 and Nanog were detected in some malignant tumors. In this study we demonstrated that stromal cells prepared from the basal cell carcinoma are able to induce ex...
ORGANISM(S): Homo sapiens 
2011-11-02 | E-MTAB-272 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human fibroblasts from the stroma of squamous cell carcinoma and normal dermal fibroblasts
Head and neck squamous cancer stromal fibroblasts produce growth factors influencing phenotype of normal human keratinocytes. Epithelial-mesenchymal interaction between stromal fibroblasts and cancer cells influences the functional properties of tumor epithelium including the tumor progression and s...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-MTAB-97 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of serum mRNA in patients with head and neck squamous cell carcinoma
With the increasing demand for non-invasive approaches in monitoring of head and neck cancer, circulating nucleic acids have been shown to be a promising tool. We focused on the global transcriptome of serum samples of HNSCC patients in comparison to healthy individuals. We compared gene expression ...
ORGANISM(S): Homo sapiens 
2014-02-20 | E-MTAB-1516 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human neural crest-originated stem cells, BLM melanoma cell line and neonatal highly pigmented melanocytes to study their production of extracellular factors.
Analysis of microarrays with transcriptome of human neural crest-originated stem cells (NCSC), highly metastatic BLM melanoma cell line and neonatal highly pigmented melanocytes (HPM) at whole genome scale demonstrated distinct differences among tested cell types.
ORGANISM(S): Homo sapiens 
2015-12-09 | E-MTAB-2401 | biostudies-arrayexpress
TranscriptomicsActivation of normal dermal fibroblasts by normal and cancer epithelial cells: clinical samples.
We model processes of wound healing and tumor growth, by studying the effects of normal and cancer epithelial cells on normal fibroblasts and their reciprocal effect on normal keratinocytes in vitro. We find strong parallels between the two processes and compare our observations with transcriptional...
ORGANISM(S): Homo sapiens 
2013-11-02 | E-MTAB-1065 | biostudies-arrayexpress
TranscriptomicsActivation of normal dermal fibroblasts by normal and cancer epithelial cells. Tissue cultures.
We model processes of wound healing and tumor growth, by studying the effects of normal and cancer epithelial cells on normal fibroblasts and their reciprocal effect on normal keratinocytes in vitro. We find strong parallels between the two processes and compare our observations with transcriptional...
ORGANISM(S): Homo sapiens 
2013-11-02 | E-MTAB-1064 | biostudies-arrayexpress
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