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Primary cilia are microtubule based sensory organelles important for receiving and processing cellular signals. Recent studies have shown that cilia also release extracellular vesicles (EVs) but little is known about their composition and function. Because EVs have been shown to exert various functi...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-19 | PXD020466 | Pride
This study aims to investigate the role of Streptococcus mutans–derived extracellular vesicles (SmEVs) in the progression of oral squamous cell carcinoma (OSCC). We integrated transcriptomics and DIA-based quantitative proteomics to systematically analyze changes in gene expression in CAL-27 cells a...
ORGANISM(S): Streptococcus Mutans 
2025-12-23 | PXD072344 |
Oral squamous cell carcinoma (OSCC) is an aggressive malignancy in which microbial dysbiosis is increasingly recognized as a contributing factor, yet the pathogenic potential of bacterial extracellular vesicles (EVs) remains poorly defined. To determine whether Streptococcus mutans–derived EVs (SmEV...
ORGANISM(S): Homo sapiens 
2026-04-09 | GSE315030 | GEO
Bacterial extracellular vesicles from Streptococcus mutans drive OSCC progression through β-catenin signaling
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