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MetabolomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Multi-omics analyses are increasingly employed in microbiome studies to obtain a holistic view of molecular changes occurring within microbial communities exposed to different conditions. However, it is not always clear to what extent each omics data type contributes to our understanding of the comm...
2022-12-08 | MTBLS3129 | MetaboLights
TranscriptomicsChromatin immunoprecipitation and DNAse I hypersensitive site mapping of mouse hematopoietic cell lines and tissue-types to identify histone modification and transcription factor binding sites
Histone modification and transcription factor ChIP-chip in hematopoietic cell lines and tissue-types
ORGANISM(S): Mus musculus 
2008-09-30 | E-TABM-455 | biostudies-arrayexpress
TranscriptomicsWhole embryo RNA-seq of 73 mouse mutant lines and baseline controls from the Mouse Genetics Project (DMDD)
The Deciphering the Mechanisms of Developmental Disorders (DMDD) programme analyses the morphological and molecular phenotypes of embryonic and perinatal lethal mouse mutant lines. Here we show that single whole embryo RNA-seq of 73 mouse mutant lines (>1000 transcriptomes) uncovers transcriptional ...
ORGANISM(S): Mus musculus 
2019-10-31 | E-MTAB-7322 | biostudies-arrayexpress
MetabolomicsSuccinate accumulation drives ischaemia-reperfusion injury during organ transplantation
During heart transplantation, storage in cold preservation solution is thought to protect the organ by slowing metabolism; by providing osmotic support; and by minimising ischaemia-reperfusion (IR) injury upon transplantation into the recipient. Despite its widespread use, our understanding of the m...
2019-09-20 | MTBLS1085 | MetaboLights
UnknownOpposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism
Not available
S-SCDT-EMM-2018-09711 | biostudies-other
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