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Elevated brain levels of the essential metals manganese (Mn), copper, or iron induce motor disease. However, mechanisms of metal-induced motor disease are unclear and treatments are lacking. Elucidating the mechanisms of Mn-induced motor disease is particularly important because occupational and env...
2025-03-31 | MTBLS975 | MetaboLights
This experiment consists of two studies. The first where two independent biological replicates of MG1655, MG1655 thyA suhB::thyA and MG1655 thyA nusB::thyA were each grown in LB to mid-exponential phase. RNA-seq and associated data analysis were performed as described previously (Stringer et al., 20...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
A copy-number variation (CNV) analysis was run on 40 CEU and YRI samples across an array set tiling across the human genome. The array contained 42 million oligos spread across 20 arrays. The final design provided 1 probe per 50bp average density across the genome.

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ORGANISM(S): Homo sapiens 
We conducted comparative genome hybridization experiments to catalogue the common copy number variation evident between 269 individuals from three geographically distinct human populations (Yoruban, Chinese/Japanese, European) against a single reference individual.
ORGANISM(S): Homo sapiens 
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