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TranscriptomicsGene expression profiling of individual human oocytes and embryos
Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic ...
ORGANISM(S): Homo sapiens 
2013-12-13 | E-MEXP-3870 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Xenopus tropicalis tadpole tail tissue regeneration following removal
In this experiment, we show transcription profiling of the Xenopus tropicalis tadpole tail tissue regeneration following removal. The tail tissues include its spinal cord, notochord, muscle, and dorsal aorta. We characterized the early, intermediate, and late stages of Xenopus tropicalis tail regene...
ORGANISM(S): Xenopus tropicalis 
2010-10-01 | E-MEXP-2420 | biostudies-arrayexpress
UnknownThe Art of Designing DNA Nanostructures with CAD Software.
Not available
S-EPMC8071251 | biostudies-literature
TranscriptomicsGpx3 male transgenic liver expression vs B6/DBA male wildtype control
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-11997 | biostudies-arrayexpress
UnknownImmune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station.
Not available
S-EPMC10992860 | biostudies-literature
UnknownAccelerated functional brain aging in pre-clinical familial Alzheimer's disease.
Not available
S-EPMC8429427 | biostudies-literature
TranscriptomicsObesity study in transgenic and knockout animals
A major task in dissecting the genetics of complex traits is to identify causal genes for disease phenotypes. We previously developed a method to infer causal relationships among genes through the integration of DNA variation, gene transcription, and phenotypic information. Here we validated our m...
ORGANISM(S): Mus musculus 
2009-03-07 | E-GEOD-12000 | biostudies-arrayexpress
TranscriptomicsFine-Scale Mapping and Sequencing of Structural Variation from Eight Human Genomes
Genetic variation amongst individual humans occurs on many different scales, ranging from gross alterations in the human karyotype to single-nucleotide changes. In this manuscript we explore variation on an intermediate scale-particularly insertions, deletions, and inversions affecting from a few t...
ORGANISM(S): Homo sapiens 
2008-05-01 | E-GEOD-10008 | biostudies-arrayexpress
UnknownInsulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains.
Not available
S-EPMC11068109 | biostudies-literature
TranscriptomicsRNA-Seq of Single Prostate CTCs Implicates Non-Canonical Wnt Signaling in Antiandrogen Resistance
Prostate cancer is initially responsive to androgen deprivation, but the effectiveness of androgen receptor (AR) inhibitors in recurrent disease is variable. Biopsy of bone metastases is challenging, hence sampling circulating tumor cells (CTCs) may reveal drug resistance mechanisms. We established ...
ORGANISM(S): Homo sapiens 
2015-09-17 | E-GEOD-67980 | biostudies-arrayexpress
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