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ProteomicsPRMT6 substrate specificity analysis
Protein arginine methyltransferase 6 (PRMT6) catalyses the asymmetric dimethylation of arginines on numerous substrate proteins within the human cell. In particular, PRMT6 methylates histone H3 arginine 2 (H3R2) which affects both gene repression and activation. However, the substrate specificity of...
ORGANISM(S): Homo Sapiens 
2021-03-31 | PXD016711 | panorama
ProteomicsLFQ DIA to analyze the proteome of NPC mutant iNeurons with and without ferric ammonium citrate
Label-free quantification (LFQ) using data-independent acquisition (DIA) on the Orbitrap Astral was performed to analyze the proteome of iNeurons with NPC1 and NPC2 knocked out. The experiment includes the following time points of development: day 0, 4, 8, 16, and 22. All samples were cultured in re...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000095985 | MassIVE
TranscriptomicsA methyl-deviator epigenotype of estrogen-receptor-positive breast carcinoma is associated with malignant biology
We broadly profiled DNA methylation in breast cancers (n=351) and benign parenchyma (n=47) for correspondence with disease phenotype using formalin-fixed paraffin-embedded (FFPE) diagnostic surgical pathology specimens. Exploratory analysis revealed a distinctive primary invasive carcinoma subclass ...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-29428 | biostudies-arrayexpress
TranscriptomicsOncogenic SDH mutation underlies global epigenomic instability in gastrointestinal stromal tumor
We have discovered a striking connection between mitochondrial dysfunction and epigenomic instability, manifested by global biallelic DNA cytosine 5-methylation and loss of 5-hydroxymethycytosine within succinate dehydrogenase (SDH)-null gastrointestinal stromal tumors (GIST) relative to those beari...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-34387 | biostudies-arrayexpress
ProteomicsMtruncatula - Stem, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 14.8, Coverage: 27
ORGANISM(S): 3880 
2016-00-00 | 2164794630 | PAXDB
ProteomicsMtruncatula - Root, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 13.0, Coverage: 29
ORGANISM(S): 3880 
2016-00-00 | 3047189613 | PAXDB
ProteomicsMtruncatula - Leaf, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 17.2, Coverage: 30
ORGANISM(S): 3880 
2016-00-00 | 3540523698 | PAXDB
ProteomicsMtruncatula - Flower, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 17.0, Coverage: 32
ORGANISM(S): 3880 
2016-00-00 | 2102073507 | PAXDB
ProteomicsMtruncatula - Seed, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 13.9, Coverage: 26
ORGANISM(S): 3880 
2016-00-00 | 1575946262 | PAXDB
ProteomicsMtruncatula - Bud, iBAQ (Marxetal,natbiotechnol2016)
abundance based on iBAQ, Interaction consistency score: 17.7, Coverage: 29
ORGANISM(S): 3880 
2016-00-00 | 547101395 | PAXDB
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