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For many organisms, death is a tangible, visible event. In bacteria, death can be a natural or an induced process 1. Death permits genes conferring a survival advantage to be selected in a bacterial population. Furthermore, biomolecule recycling from dead bacteria is crucial under nutrient limitatio...
2025-01-23 | MTBLS10044 | MetaboLights
The ubiquitous protein DnaA is a chromosomal DNA replication initiator and transcription factor. It binds to 9-bp DNA sites called \"DnaA-boxes\" that are localized within the replication origin (oriC) and throughout chromosomal DNA, usually in the proximity of the promoter regions. During stress, b...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
Global ChIP-chip analysis of HspR repressor binding sites in Streptomyces coelicolor MT1110 cultures grown in YEME plus 10% sucrose at 30?C up to early stationary phase. Chromatin extracted from formaldehyde treated cultures was incubated with anti HspR polyclonal antibodies and the DNA purified f...
ORGANISM(S): Streptomyces coelicolor 
Global gene expression patterns of S. coelicolor MT1151 and MT1153 (two independent MT1110 hspR disruption mutants ) cultures compared to MT1152 and MT1154 (two independent isolates of hspR+ integrants), grown on SMMS agar medium for 36 h .
ORGANISM(S): Streptomyces coelicolor 
Global gene expression patterns of MT1152 and MT1154 (two hspR+integrants of MT1110) grown on SMMS agar medium for 36 h and heat shocked at 42oC for 15 min. RNA was harvested from heat-shocked cultures and control cultures grown at 30oC and hybridized onto high density IJISS arrays to identify which...
ORGANISM(S): Streptomyces coelicolor 
Global gene expression patterns of two biological replicate cultures of S.coelicolor MT1110 grown on YEME plus 10% sucrose up to early stationary phase ( the culture conditions were the same used for obtaining ChIP-chip data with anti HspR antibodies). RNA was harvested from heat-shocked cultures ...
ORGANISM(S): Streptomyces coelicolor 

Diabetic foot infection (DFI) significantly increases risks of hospitalization and amputation, with biofilm infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE) being key drivers of treatment failure. Here, we ana...

2026-01-06 | MTBLS13603 | MetaboLights
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