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ProteomicsSynergistic targeting of DNA-PK and KIT signaling pathways in KIT mutant acute myeloid leukemia
Acute Myeloid Leukemia (AML) is the most common and aggressive form of acute leukemia, with a 5-year survival rate of just 24%. Over a third of all AML patients harbor activating mutations in kinases, such as the receptor tyrosine kinases FLT3 and KIT. FLT3 and KIT mutations are associated with poor...
ORGANISM(S): Mus Musculus 
2023-01-26 | PXD030214 | panorama
ProteomicsMining waste streams of food production for bioactive plant polysaccharides that affect the fitness and expressed activities of targeted human gut microbes
Mining waste streams of food production for bioactive plant polysaccharides that affect the fitness and expressed activities of targeted human gut microbes
ORGANISM(S): Microbiota (ncbitaxon:13613) Mus Musculus (ncbitaxon:10090) 
2018-04-18 | MSV000082287 | MassIVE
UnknownWhole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
Not available
S-EPMC3928660 | biostudies-literature
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
UnknownThe deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Not available
S-EPMC3376394 | biostudies-literature
UnknownGenetic studies of body mass index yield new insights for obesity biology.
Not available
S-EPMC4382211 | biostudies-literature
UnknownExtension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.
Not available
S-EPMC2518503 | biostudies-literature
UnknownEffects of genetic variants previously associated with fasting glucose and insulin in the Diabetes Prevention Program.
Not available
S-EPMC3439414 | biostudies-literature
UnknownTCF7L2 polymorphism, weight loss and proinsulin:insulin ratio in the diabetes prevention program.
Not available
S-EPMC3144193 | biostudies-literature
UnknownGenetic modulation of lipid profiles following lifestyle modification or metformin treatment: the Diabetes Prevention Program.
Not available
S-EPMC3431328 | biostudies-literature
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