Sort   by:  
 Page size 
MetabolomicsCTH exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation
Macrophages play a crucial role in the inflammatory response to the human stomach pathogen Helicobacter pylori, which infects half of the world's population and causes gastric cancer. Recent studies have highlighted the importance of macrophage immunometabolism in their activation state and function...
2022-06-14 | MTBLS2851 | MetaboLights
TranscriptomicsArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
RELEVANCE: Smith-Lemli-Opitz syndrome (SLOS) is a human disease caused by mutations in the gene coding for the enzyme DHCR7 (7-dehydrocholesterol (7DHC) reductase), which catalyzes the final step of cholesterol biosynthesis. Accumulated 7DHC in tissues and body fluids of SLOS patients gives rise t...
ORGANISM(S): Mus musculus 
2021-03-20 | E-MTAB-10055 | biostudies-arrayexpress
GenomicsChIP-seq analysis of human neuroblastoma cell lines
The aim of the experiment is to identify genome wide binding sites for the transcription factor MYCN in MYCN non-amplified and MYCN amplified human neuroblastoma cell lines. Datasets are presented for the ChIP-seq analysis in the tetracycline inducible cell line SH-SY5Y-MYCN (SH-SY5Y/6TR(EU)/pTrex-D...
ORGANISM(S): Homo sapiens 
2016-10-25 | E-MTAB-4100 | biostudies-arrayexpress
ProteomicsDietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration
Targeted GC-MS detection of host and dietary metabolites and modifications by gut bacteria.
ORGANISM(S): Eggerthella Lenta (ncbitaxon:84112) Holdemania Filiformis (ncbitaxon:61171) Sutterella Wadsworthensis (ncbitaxon:40545) 
2023-11-03 | MSV000093291 | MassIVE
MetabolomicsLC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study
Today's high-resolution mass spectrometers (HRMS) allow bioanalysts to perform untargeted/global determinations that can reveal unexpected compounds or concentrations in a patient’s sample. This could be performed for preliminary diagnosis attempts when usual diagnostic processes and targeted ...
2019-06-06 | MTBLS476 | MetaboLights
GenomicsH3K27Ac and H3K4me1 ChIP-seq in Rex1GFPd2 mouse embryonic stem cell line
Chromatin immunoprecipitation using H3K27Ac and H3K4me1 antibodies in Rex1GFPd2 mouse ES cells (parental line; E14Tg2a)
ORGANISM(S): Mus musculus 
2014-06-24 | E-MTAB-2282 | biostudies-arrayexpress
GenomicsOtx2 ChIP-seq in Rex1GFPd2 mouse embryonic stem cell line
Chromatin immunoprecipitation using Otx2 antibodies in Rex1GFPd2 mouse ES cells (parental line; E14Tg2a)
ORGANISM(S): Mus musculus 
2014-06-24 | E-MTAB-2281 | biostudies-arrayexpress
TranscriptomicsmRNA expression profiles of TAE-684 treated or shALK transfected neuroblastoma cell lines
Human wild-type ALK (SK-N-AS, NGP, IMR-32), ALKR1275Q (CLB-GA, LAN-5, UKF-NB-3), ALKF1174L (SK-N-SH, Kelly, SMS-KCNR) and ALK amplified (NB-1) neuroblastoma cell lines were treated in triplicate with 0.3M-k_M NPV-TAE-684 (Novartis/SelleckChem) or DMSO (VWR) for 6 hours, followed by RNA isolation and...
ORGANISM(S): Homo Sapiens 
2015-05-04 | E-MTAB-3205 | biostudies-arrayexpress
TranscriptomicsFAIRE-seq in Rex1GFPd2 mouse embryonic stem cell line
Formaldehyde-assisted isolation of regulatory elements (FAIRE) in Rex1GFPd2 mouse ES cells (parental line; E14Tg2a)
ORGANISM(S): Mus musculus 
2014-06-24 | E-MTAB-2283 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics links glutathione to bacterial cell cycle progression
Cell cycle progression requires the coordination of cell growth, chromosome replication, and division. Consequently, a functional cell cycle must be coupled with metabolism. However, direct measurements of metabolome dynamics remained scarce, in particular in bacteria. Here, we describe an untargete...
2020-10-15 | MTBLS1402 | MetaboLights
Sort   by:  
 Page size