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ORGANISM(S): Homo sapiens 
MicroRNA expression was assayed from bronchial epithelial cells collected via bronchoscopy from healthy current and never smoker volunteers in order to determine the effect of cigarette smoke exposure on airway epithelial microRNA expression Keywords: Global microRNA expression profiling Bronchial ...
ORGANISM(S): Homo sapiens 
Transcriptome analysis of primary bronchial epithelial cells from healthy, ex-smoker COPD and current smoker COPD patients cultured in ALI conditions
ATAC-seq analysis of primary bronchial epithelial cells from healthy, ex-smoker COPD and current smoker COPD patients cultured in ALI conditions
Single cell ATACseq of primary bronchial epithelial cells from healthy, ex-smoker COPD and current smoker COPD patients cultured in ALI conditions
Single cell RNAseq of primary bronchial epithelial cells from healthy, ex-smoker COPD and current smoker COPD patients cultured in ALI conditions
Chronic obstructive pulmonary disease (COPD) is one of the most prevalent lung diseases, and involves persistent airflow limitation and incorporates both emphysema and chronic bronchitis. Cigarette smoking has been identified as the main risk factor for disease development and progression. In a basi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080275 | MassIVE
Rationale: Genome-wide association studies (GWAS) and candidate gene studies have identified a number of loci linked to susceptibility of chronic obstructive pulmonary disease (COPD), a smoking-related disorder that originates in the airway epithelium. Objectives: Since airway basal cell (BC) stem/p...
ORGANISM(S): Homo sapiens 
Approximately 15% of lung cancer cases are not associated with smoking and show molecular and clinical characteristics distinct from those in smokers. Epidermal growth factor receptor (EGFR) gene mutations, which are correlated with sensitivity to EGFR-tyrosine kinase inhibitors (EGFR-TKIs), are mo...
ORGANISM(S): Homo sapiens 
mRNA expression was assayed from bronchial epithelial cells collected via bronchoscopy and nasal epithelial cells collected by brushing the inferior turbinate from healthy current and never smoker volunteers in order to determine the relationship between smoking-related gene expression changes in b...
ORGANISM(S): Homo sapiens 
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