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MetabolomicsMetabolically-incorporated deuterium in myelin localized by neutron diffraction and identified by mass spectrometry
Myelin is a natural and dynamic multilamellar membrane structure that continues to be of significant biological and neurological interest, especially with respect to its biosynthesis and assembly during its normal formation and maintenance, and pathological breakdown. To explore the usefulness of ne...
2024-09-27 | MTBLS4717 | MetaboLights
MetabolomicsMetabolic adaptation of diatoms to hypersalinity

Microalgae are important primary producers and form the basis for the marine food web. As global climate changes, so do salinity levels that algae are exposed to. A metabolic response of algal cells partly alleviates the resulting osmotic stress. Some metabolites involved in the response are well...

2023-09-04 | MTBLS3177 | MetaboLights
TranscriptomicsTranscriptomic analyses of duodenum from wild type and VDR-null mice
As duodenum is an important Vitamin D target organ, transcriptomic analyses were performed in this tissue. We analysed RNA extracted from duodenum of three 10 week-old wild-type and VDR-null mice using the Affymetrix Mouse Gene 2.0 ST.
ORGANISM(S): Mus musculus 
2015-04-16 | E-GEOD-67904 | biostudies-arrayexpress
MetabolomicsGNPS_Sorangium cellulosum So ce38 and So ceGT47, various media, auto-MS2 and SPL-MS2
MS2 data set resulting from the SPL-MS2 method development as described in the publication mentioned below. The data set is based on triplicate measurements (technical) of various extracts. Extracts are mixtures of three biological replicates (see publication for explanation). In addition, blank ext...
ORGANISM(S): Sorangium Cellulosum So Ce38 Sorangium Cellulosum So Cegt47 
2014-12-07 | MSV000078960 | GNPS
UnknownLife based on phosphite: a genome-guided analysis of Desulfotignum phosphitoxidans.
Not available
S-EPMC4046663 | biostudies-literature
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [double KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68725 | biostudies-arrayexpress
TranscriptomicsSynergism of calcium sensing receptor and vitamin D receptor mediated signaling in epidermal differentiation [VDR KO]
Calcium and 1,25-dihydroxyvitamin D3 (1,25D3), through the actions of their respective receptors, the Ca2+-sensing receptor (CaSR) and the vitamin D receptor (VDR), potentiate keratinocyte differentiation. VDR regulates epidermal keratinocyte proliferation and differentiation by modulating gene tran...
ORGANISM(S): Mus musculus 
2015-07-31 | E-GEOD-68723 | biostudies-arrayexpress
UnknownBacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS.
Not available
S-EPMC10848231 | biostudies-literature
MetabolomicsNon-targeted in vitro metabolomics for proteome-scale identification of novel enzymes in Escherichia coli
Many yet undiscovered enzymes still limit our understanding of metabolism. Here, we develop a high-throughput mass spectrometry approach to comprehensively profile proteome-scale protein collections for in vitro enzymatic activity. Overexpressed or purified proteins are incubated in a supplemented m...
2016-01-11 | MTBLS373 | MetaboLights
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