Sort   by:  
 Page size 
MetabolomicsMass spectrometry based metabolomics for in vitro systems pharmacology: Pitfalls, challenges, and computational solutions

INTRODUCTION: Mass spectrometry based metabolomics has become a promising complement and alternative to transcriptomics and proteomics in many fields including in vitro systems pharmacology. Despite several merits, metabolomics based on liquid chromatography mass spectrometry (LC...

2017-08-23 | MTBLS401 | MetaboLights
MetabolomicsMetabolome analysis via an HPLC-ESI-MS-based experimental and computational pipeline for chronic nephron toxicity profiling
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
MetabolomicsProMetIS, deep phenotyping of mouse models by combined proteomics and metabolomics analysis

Genes are pleiotropic and getting a better knowledge of their function requires a comprehensive characterization of their mutants. Here, we generated multi-level data combining phenomic, proteomic and metabolomic acquisitions from plasma and liver tissues of two C57BL/6 N mouse models lacking the...

2021-09-01 | MTBLS1903 | MetaboLights
UnknownMASH Suite Pro: A Comprehensive Software Tool for Top-Down Proteomics.
Not available
S-EPMC4739683 | biostudies-literature
UnknownSoftware platform for rapidly creating computational tools for mass spectrometry-based proteomics.
Not available
S-EPMC2696634 | biostudies-literature
UnknownMaxQuant Software for Ion Mobility Enhanced Shotgun Proteomics.
Not available
S-EPMC7261821 | biostudies-literature
ProteomicsMaxQuant software for ion mobility enhanced shotgun proteomics
Ion mobility can add a dimension to LC-MS based shotgun proteomics which has the potential to boost proteome coverage, quantification accuracy and dynamic range. Required for this is suitable software that extracts the information contained in the four-dimensional (4D) data space spanned by m/z, re...
ORGANISM(S): Homo sapiens (Human) Escherichia coli Saccharomyces cerevisiae (Baker's yeast) 
2020-04-23 | PXD014777 | Pride
Tims Human Yeast Maxquant Hela Ecoli 
Unknowncompomics-utilities: an open-source Java library for computational proteomics.
Not available
S-EPMC3060842 | biostudies-literature
Proteomics,MultiomicsDIA-Umpire: comprehensive computational framework for data independent acquisition proteomics
This dataset consists of 44 raw MS files, comprising 27 DIA (SWATH) and 15 DDA runs on a TripleTOF 5600 and of two raw mass spectrometry files acquired on a Q Exactive. The composition of the dataset is described in the manuscript by Tsou et al., titled: "DIA-Umpire: comprehensive computational fra...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2017-04-27 | MSV000081023 | MassIVE
MetabolomicsModel-guided development of evolutionarily stable yeast chassis for dicarboxylic acids production

Chassis strain suitable for producing multiple compounds is a central concept in synthetic biology. Design of a chassis using computational, first-principle, models is particularly attractive due to the predictability and control it offers, including against phenotype reversal due to adaptive mut...

2021-07-19 | MTBLS2007 | MetaboLights
Sort   by:  
 Page size