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ProteomicsIntegrative proteogenomics for differential expression and splicing variation in a DM1 mouse model
Here, we performed a large-scale coordinated transcriptomic and proteomic analysis to characterize a DM1 mouse model (HSALR) in comparison to wild-type. Our integrative proteogenomics approach comprised gene- and splicing-level assessments for mRNA and protein. It recapitulated many known instances ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD025589 | Pride
Mouse model Proteogenomics Transcriptomics Alternative splicing Proteomics Myotonic dystrophy type 1 (dm1) 
ProteomicsComparative proteomics for identification of type I interferon response in primary human glioblastoma multiforme cells
Oncolytic virus therapy is a promising direction for cancer treatment. Numerous oncolytic virus strains are under development or examined in clinical trials, there are examples of FDA approved virus vaccines. Although evident progress exists, oncolytic viruses still suffer low efficiency and the mec...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD022836 | Pride
Glioblastoma Proteomics Interferone response Lc-ms/ms Oncolytic viruses 
ProteomicsComparative proteomics for identification of type I interferon response in primary human glioblastoma multiforme cells
Oncolytic virus therapy is a promising direction for cancer treatment. Numerous oncolytic virus strains are under development or examined in clinical trials, there are examples of FDA approved virus vaccines. Although evident progress exists, oncolytic viruses still suffer low efficiency and the mec...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD022906 | Pride
Glioblastoma Proteomics Interferone response Lc-ms/ms Oncolytic viruses 
ProteomicsExome-based proteogenomics of HEK-293 human cell line: coding genomic variants identified at the level of shotgun proteome
Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK-293) standard cell line at the proteome level. Shotgun proteome data published by Geiger et al (2012) and obtained in this work for HEK-293 were searched ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080712 | MassIVE
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