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TranscriptomicsTranscription profiling of livers from SCD1 knockout and wild type mice to elucidate the molecular basis of protection against adiposity in mice lacking of stearoyl-CoA desaturase-1 function
Stearoyl-CoA desaturase (SCD) is a central lipogenic enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are components of membrane phospholipids, triglycerides, wax esters, and cholesterol esters. Several SCD isoforms (SCD1-3) exist ...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2926 | biostudies-arrayexpress
TranscriptomicsMapping the binding regions of the cubitus interruptus (Ci) activator form
Paracrine Hedgehog (Hh) signaling regulates growth and patterning in many Drosophila organs. We mapped chromatin binding sites for Cubitus interruptus (Ci), the transcription factor that mediates outputs of Hh signal transduction, and we analyzed transcription profiles of control and mutant embryos...
ORGANISM(S): Drosophila melanogaster 
2010-11-03 | E-GEOD-23999 | biostudies-arrayexpress
TranscriptomicsMapping the binding regions of the cubitus interruptus (Ci) repressor form
Paracrine Hedgehog (Hh) signaling regulates growth and patterning in many Drosophila organs. We mapped chromatin binding sites for Cubitus interruptus (Ci), the transcription factor that mediates outputs of Hh signal transduction, and we analyzed transcription profiles of control and mutant embryos...
ORGANISM(S): Drosophila melanogaster 
2010-11-03 | E-GEOD-24024 | biostudies-arrayexpress
TranscriptomicsIdentification of genetic targets of Hh signaling in Drosophila
Paracrine Hedgehog (Hh) signaling regulates growth and patterning in many Drosophila organs. We mapped chromatin binding sites for Cubitus interruptus (Ci), the transcription factor that mediates outputs of Hh signal transduction, and we analyzed transcription profiles of control and mutant embryos...
ORGANISM(S): Drosophila melanogaster 
2010-11-03 | E-GEOD-24028 | biostudies-arrayexpress
TranscriptomicsAlterations in the transcriptome and antibiotic susceptibility of Staphylococcus aureus grown in the presence of diclofenac
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which has been shown to increase the susceptibility of various bacteria to antimicrobials and demonstrated to have broad antimicrobial activity. This study describes transcriptome alterations in S. aureus strain COL grown with diclofenac ...
ORGANISM(S): Staphylococcus aureus subsp. aureus COL 
2011-07-18 | E-GEOD-30724 | biostudies-arrayexpress
Genomics32c6825c-80c0-4d0f-9284-cc7c1a39e68a - samples
Whole transcriptome sequencing (RNA-seq) was performed on 39 PC specimens. Among them, 21 specimens also had WES data.
EGAD00001004365 | EGA
Genomicsc9d38693-41de-4186-90c3-5e52d1913254 - samples
Whole-exome sequencing (WES) was performed on a total of 34 PC specimens, with 15 cases having matched gDNAs extracted from blood.
EGAD00001004364 | EGA
GenomicsProfiling of Peritoneal Metastases from Gastric Adenocarcinoma Identified Molecular Subtypes
Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune...
EGAS00001003180 | EGA
GenomicsData Access Commitee for gastric cancer ascites
Data Access Committee EGAC00001001026
EGAC00001001026 | EGA
TranscriptomicsTranscriptomics and Metabolomics of 10 - 28 day post anthesis cotton fiber from Gossypium hirsutum and Gossypium barbadense
Purpose: The goal of this experiment was to use RNA-seq to compare the two commercial cotton species Gossypium hirsutum and Gossypium barbadense and determine what transcripts may account for the better fiber quality in the latter. Methods: RNA was extracted from Gossypium barbadense or Gossypium hi...
ORGANISM(S): Gossypium barbadense 
2015-06-26 | E-GEOD-64958 | biostudies-arrayexpress
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