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UnknownRapid tryptic peptide mapping of human serum albumin using DI-MS/MSALL.
Not available
S-EPMC8963265 | biostudies-literature
UnknownQuality Analysis of American Ginseng Cultivated in Heilongjiang Using UPLC-ESI--MRM-MS with Chemometric Methods.
Not available
S-EPMC6225424 | biostudies-literature
MetabolomicsMetabolic profiling of Candida clinical isolates of different species and infection sources

Candida species are the most common cause of opportunistic fungal infections. Rapid identification and novel approaches for the characterization of these fungi are of great interest to improve the diagnosis and the knowledge about their pathogenic properties. This study aimed to characte...

2024-07-09 | MTBLS1978 | MetaboLights
MetabolomicsIn Vitro and In Vivo Metabolomic Profiling after Infection with Virulent Newcastle Disease Virus
Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights
ProteomicsProteome of mass-produced Escherichia coli outer membrane vesicles
Large-scale production of bacterial extracellular vesicles is a hurdle for their development as novel cancer immunotherapeutic agents. Here, we developed manufacturing processes for mass production of Escherichia coli EVs known as outer membrane vesicles (OMVs). We present a comprehensive proteome o...
ORGANISM(S): Escherichia coli Bacteria 
2023-10-24 | PXD043119 | Pride
Escherichia coli Outer membrane vesicles Mass production Lc-ms/ms 
UnknownA SARS-CoV-2 M<sup>pro</sup> mutation conferring ensitrelvir resistance paradoxically increases nirmatrelvir susceptibility.
Not available
S-EPMC12663368 | biostudies-literature
MetabolomicsEnterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance
Commensal intestinal bacteria play key roles in regulating cells mediating immune tolerance; however, bacterial strains and related metabolites directly involved in this regulation are largely unknown. Here, using a mouse model of dextran sulfate sodium (DSS)-induced colitis combined with different ...
2024-08-05 | MTBLS5585 | MetaboLights
MetabolomicsMyeloid PFKFB3-mediated glycolysis promotes kidney fibrosis
Excessive renal fibrosis is a common pathology in progressive chronic kidney diseases. Inflammatory injury and aberrant repair processes contribute to the development of kidney fibrosis. Myeloid cells, particularly monocytes/macrophages, play a crucial role in kidney fibrosis by releasing their proi...
2024-03-12 | MTBLS8278 | MetaboLights
ProteomicsCRL2ZER1/ZYG11B recognizes small N-terminal residues for degradation
N-degron pathway plays an important role in the protein quality control and maintenance of cellular protein homeostasis. ZER1 and ZYG11B, the substrate receptors of the Cullin 2-RING E3 ubiquitin ligase (CRL2), recognize N-terminal (Nt) glycine degrons and participate in the Nt-myristoylation qualit...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037312 | Pride
N-terminal acetylation Nt-ser Crl2zer1/zyg11b 
ProteomicsTargeting G9a Regulated m6A Modification Pathway to Hinder SARS-CoV-2 Replication
N6-methyladenosine (m6A) modification pathway is hijacked by several RNA viruses, including SARS-CoV-2, making it an attractive host-directed target for development of broad-spectrum antivirals. Here, we show that histone methyltransferase G9a, through its interaction with METTL3, regulates SARS-CoV...
ORGANISM(S): Homo sapiens (Human) 
2025-04-14 | PXD058743 | Pride
Covid-19 Sars-cov-2 
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