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TFRD has been widely used in China to treat osteoporosis (OP). However, the specific molecular mechanism of TFRD against OP has not been fully clarified. Our previous studies have also proved that TFRD could attenuate OP and the clinical equivalent dose of 67.5 mg/kg/d is the effective dose for T...

2025-05-12 | MTBLS11866 | MetaboLights
Protein lysates were derived from HEK293T cells and spermatogonial stem cells,and interacting proteins were “pulled-down” for analysis by gel electrophoresis and identification by mass spectrometry. An equal amount of non-specific IgG from rabbit serum (Thermos Fisher Scientific) was used as a negat...
ORGANISM(S): Homo Sapiens Mus Musculus 
To investigate the role of DDX20 in spermatogenesis, we generated Ddx20 flox/flox Ddx4-Cre mice to make a germ cell-specific Ddx20 knockout, and isolated spermatogonia from four-day-old mouse testes by THY1 magnetic beads. We then performed proteomic analysis using protein lysates obtained from THY1...
ORGANISM(S): Mus Musculus 
We redefined AMS by using the combination of Olink’s antibody-based proximity extension assay and the multiple reaction monitoring mass spectrometry proteome with 106 paired plasma samples of Chinese Han, 22 AMS-related phenotypes, and 65 clinical indexes. We revealed a systematic proteomic and clin...
ORGANISM(S): Homo Sapiens 
Assassin bugs are one of the diversified groups of venomous predatory insects. Their venom is secreted from three different lumens of salivary gland and can lead to paralysis, lethality and liquidation of the prey, respectively. Nevertheless, the venom components responsible for these effects are no...
ORGANISM(S): Platymeris Biguttatus 
2022-02-06 | PXD031473 |
Zinc is an essential trace element that is closely related to learning and memory ability. The hippocampus plays an important role in learning and memory and has the highest zinc concentration in the brain. Severe zinc deficiency (zinc-deprived diet) significantly alter hippocampal protein expressio...
ORGANISM(S): Rattus Norvegicus 
Zinc is an essential trace micronutrient and exerts important physiological and biochemical roles. Zinc deficiency is a global public-health problem. Standing untreated zinc deficiency can cause series adverse effects, including growth retardation, poor appetite, delayed sexual development, impaired...
ORGANISM(S): Rattus Norvegicus 
2019-06-05 | PXD014079 |
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