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ProteomicsCrotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch
Post-translational modifications of proteins are crucial to the regulation of their activity and function. As a newly discovered acylation modification, crotonylation of non-histone proteins remains largely unexplored, particularly in human embryonic stem cells (hESCs). Here we report the investigat...
ORGANISM(S): Homo sapiens (Human) 
2022-10-27 | PXD027007 | Pride
Hescs 
ProteomicsA BioID-mediated proximity-labeling of human DTX2
To identify human DTX2 proximal proteome, the BioID-DTX2 fusion protein was expressed in DTX2 KO HeLa cells. The biotinylated proteins were pulled down and subjected to mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
2022-10-11 | PXD023795 |
ProteomicsRheb and TRF1 PhastID mass spectrometric data
Rheb is a small G protein that functions as the direct activator of the mechanistic target of rapamycin complex 1 (mTORC1) to coordinate signaling cascades in response to nutrients and growth factors. Despite extensive studies, the guanine nucleotide exchange factor (GEF) that directly activates Rhe...
ORGANISM(S): Homo Sapiens 
2022-09-29 | PXD037078 |
UnknownA Comprehensive Pan-Cancer Analysis of the Potential Biological Functions and Prognosis Values of RICTOR.
Not available
S-EPMC10298440 | biostudies-literature
UnknownComprehensive RNA-Seq Analysis Pipeline for Non-Model Organisms and Its Application in Schmidtea mediterranea.
Not available
S-EPMC10218480 | biostudies-literature
UnknownComparison of volatile and nonvolatile metabolites in green tea under hot-air drying and four heat-conduction drying patterns using widely targeted metabolomics.
Not available
S-EPMC10534119 | biostudies-literature
UnknownOncogenic Kinase-Induced PKM2 Tyrosine 105 Phosphorylation Converts Nononcogenic PKM2 to a Tumor Promoter and Induces Cancer Stem-like Cells.
Not available
S-EPMC5932213 | biostudies-literature
UnknownGenetic screening reveals an essential role of p27kip1 in restriction of breast cancer progression.
Not available
S-EPMC2412956 | biostudies-literature
UnknownRosa roxburghii Fruit Extracts Upregulate Telomerase Activity and Ameliorate Cell Replicative Senescence.
Not available
S-EPMC11171777 | biostudies-literature
UnknownmTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts.
Not available
S-EPMC6917584 | biostudies-literature
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