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Hepatocellular carcinoma (HCC) poses a severe threat to human health. The NET-1 protein has been proved to be strongly associated with HCC proliferation and metastasis in our previous study. Here, we established and validated NET-1 siRNA nanoparticles system to conduct targeted gene therapy of HCC x...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020763 | Pride
Evaluation the targeted nanobubbles mediated LND against hepatocellular carcinoma by sonodynamic therapy with RNA-Seq
Sonodynamic therapy is an important approach in the treatment of hepatocellular carcinoma. A novel targeted nanobubbles loaded with HMME and LND was structured as sensibilizer, characterized the properties, and studied therapeutic effect on hepatocellular carcinoma. Next-generation high throughput R...
ORGANISM(S): Homo sapiens 
2022-03-02 | GSE171857 | GEO
Non-surgical treatment for endometrial cancer is limited by poor tumor targeting and the immunosuppressive microenvironment of conventional progesterone-based therapies. Emerging evidence highlights the therapeutic potential of targeting calcium homeostasis, while advances in nanomedicine enable the...
ORGANISM(S): Homo sapiens 
2026-10-07 | GSE325161 | GEO
Near Infrared Fluorescent Iridium Nanoparticles for Immunogenic Sonodynamic Therapy
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