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Transcriptomicstranscriptome analysis of SIRT2 dependent genes modulated during infection by Listeria monocytogenes
tissue culture cells were treated with an inhibitor to the deacetylase SIRT2 (AGK2) and infected with Listeria monocytogenes
ORGANISM(S): Homo sapiens 
2013-06-01 | E-MEXP-3912 | biostudies-arrayexpress
TranscriptomicsDistinct Transcriptional Signatures of Bone Marrow-Derived C57BL/6 and DBA/2 Dendritic Leucocytes Hosting Live Leishmania amazonensis Amastigotes
To determine the modulation of gene expression of C57BL/6 and DBA/2 BMDLs in the presence of living intracellular Leishmania amazonensis amastigotes A genome-wide transcriptional analysis was performed by comparing the gene expression profiles of control DLs and live amastigote-hosting DLs from bot...
ORGANISM(S): Mus musculus 
2013-01-07 | E-GEOD-38261 | biostudies-arrayexpress
TranscriptomicsSumoylation at Chromatin Governs Coordinated Repression of a Transcriptionnal Program Essential for Cell Growth and Proliferation
mRNA profiling of WI38 wild-type or overexpressiong the SUMO E3 ligase PIASy in human primary fibroblasts 24h post-infection. The goal of this study is to analyse transcriptional changes in cells over-expressing the SUMO E3 ligase PIASy and to compare them with ChIPseq data for several histones mark...
ORGANISM(S): Homo sapiens 
2013-11-25 | E-MEXP-3776 | biostudies-arrayexpress
TranscriptomicsSumoylation at Chromatin Governs Coordinated Repression of a Transcriptionnal Program Essential for Cell Growth and Proliferation 3
mRNA profiling of WI38 expressing shCt or shUbc9 4 days post-infection. The goals of this study is to analyse transcriptionnal changes in cells were sumoylation pathway is inactivated and to compare them with ChIPseq data for several histones marks and proteins of the SUMO machinery.
ORGANISM(S): Homo sapiens 
2013-11-25 | E-MEXP-3778 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Fibroblasts of Sanfilippo syndrome type B patient
Gene expression profiling of human fibroblasts from patients with Sanfilippo syndrome type B (MPSIIIB) before and after correction of the Alpha N-acetylglucosaminidase (NAGLU) enzyme defect.
ORGANISM(S): Homo sapiens 
2011-03-15 | E-MEXP-3033 | biostudies-arrayexpress
TranscriptomicsSumoylation at Chromatin Governs Coordinated Repression of a Transcriptionnal Program Essential for Cell Growth and Proliferation 2
mRNA profiling of proliferative versus Ras-induced senescent human primary fibroblasts 5 days post-infection. The goals of this study is to analyse transcriptional changes in senescent cells (RASv12 infected cells)
ORGANISM(S): Homo sapiens 
2013-11-25 | E-MEXP-3777 | biostudies-arrayexpress
TranscriptomicsTranscriptome of M. tuberculosis-infected human macrophages in the presence of ATP
Human monocyte-derived macrophages were infected with Mycobacterium tuberculosis (H37Rv strain) at a multiplicity of infection 1:1. After 2h of incubation, cells were washed to remove extracellular bacteria and were incubated in fresh medium for a further 18h in the presence or not of 100microM ATP....
ORGANISM(S): Homo sapiens 
2013-06-01 | E-MEXP-3805 | biostudies-arrayexpress
TranscriptomicsTranscriptome expression profile of primary mouse embryonic fibroblasts (MEFs) from BAHD1+/+ (WT) and BAHD1-/- (KO) mice
Comparisons of gene expression profiles of BAHD1-KO MEFs to those of wild-type MEFs (sampled at embryonic day E13.5). We used DNA microarrays to identify the repertoire of genes differentially expressed by ablation of the BAHD1 gene in mouse embryonic fibroblasts.
ORGANISM(S): Mus musculus 
2016-03-15 | E-GEOD-73816 | biostudies-arrayexpress
TranscriptomicsTranscriptome expression profile of embryonic liver and placenta tissue from BAHD1+/+ (WT) and BAHD1-/- (KO) mice at embryonic day E16.5
Comparisons of embryonic liver and placenta gene expression profiles of BAHD1-KO mice to those of wild-type littermate mice We used DNA microarrays to identify the repertoire of genes differentially expressed by ablation of the BAHD1 gene in embryos.
ORGANISM(S): Mus musculus 
2016-03-15 | E-GEOD-53442 | biostudies-arrayexpress
TranscriptomicsTranscriptome of HEK293 cells (HEK293-CT) and HEK293 cells stably over-expressing the BAHD1 gene (HEK-BAHD1)
Comparison of gene expression profile of HEK293-CT cells and HEK293 cells stably over-expressing the BAHD1 gene (HEK-BAHD1) We used micrarrays to identify the repertoire of genes differentially expressed upon overexpression of the chromatin repressor BAHD1 in HEK293 cells.
ORGANISM(S): Homo sapiens 
2015-12-11 | E-GEOD-51863 | biostudies-arrayexpress
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