Sort   by:  
 Page size 
ProteomicsChronic pain susceptibility is associated with anhedonic behavior and alterations in the accumbal ubiquitin-proteasome system
It remains unknown why upon similar acute/subacute painful conditions, pain persists in some individuals while in others it resolves. Genetic factors, mood, and functional alterations, particularly involving the mesolimbic network, appear to be key. In order to explore potential susceptibility/resis...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-04-27 | PXD022478 | Pride
Neuropathic pain  allodynia  proteomic screening  nucleus accumbens  resistance  proteasome 
ProteomicsKinetochores read detyrosinated tubulin to sustain microtubule attachments
Post-translational cycles of α-tubulin detyrosination/tyrosination generate microtubule diversity, with broad physiological and clinical implications. However, the mechanistic understanding of how this microtubule diversity is decoded into specific cellular functions remains largely unknown. Here we...
ORGANISM(S): Homo sapiens (Human) 
2024-10-03 | PXD047133 | Pride
Kinetochore microtubule attachments Tubulin detyrosination/tyrosination code Kmn complex 
ProteomicsBeta-Adrenergic stimulation of breast cancer MDA-MB-231 and bone tropic MDA-MB-231-BoM 1833 cell line secretome
In this study, we aimed to study the effect of Beta-2 Adrenergic Receptor stimulation on secreted proteins in triple negative breast cancer cell lines. We also wanted to compare protein expression in parental or bone tropic metastatic cell lines and how they respond to adrenergic signaling.
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD030371 | Pride
Human Lc-msms Breast cancer Conditioned medium Secreted 
ProteomicsA comprehensive overview to understand the dynamic R2SP complex.
Here, we used molecular biological, biochemical, biophysical and structural approaches to describe the human R2SP complex, that reveal similarities as well as significant differences compared to canonical R2TP and hints towards its specific mode of assembly and action. Cross-linking mass spectrometr...
ORGANISM(S): Escherichia coli 
2026-02-13 | PXD056494 | Pride
Proteomics Cross-linking mass spectrometry Structural biology 
UnknownElective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans.
Not available
S-EPMC7272903 | biostudies-literature
Sort   by:  
 Page size