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Dysregulated proteolysis plays a pivotal role in the pathophysiology of inflammatory bowel disease. Nonetheless, the identity of overactive proteases released by human colonic mucosa remains unknown. Herein, we employed a serine protease-targeted activity-based probe (ABP) coupled with mass spectral...
ORGANISM(S): Homo sapiens (Human) 
2018-05-18 | PXD009450 | Pride
The PII family comprises a group of widely distributed signal transduction proteins ubiquitous present in prokaryotes and in the chloroplast of plants. The PII proteins sense the levels of key metabolites ATP, ADP and 2-oxoglutarate which affect the PII structure and the ability of PII to interact w...
ORGANISM(S): Azospirillum brasilense Sp245 
2020-10-23 | PXD018530 | Pride
Acanthoscurria gomesiana is a Brazilian spider from the Theraphosidae family inhabiting regions of Southeastern Brazil. Potent antimicrobial peptides as gomesin and acanthoscurrin have been discovered from the spider hemolymph in previous works. Spider venoms are also recognized as sources of biolog...
ORGANISM(S): Acanthoscurria gomesiana (Tarantula spider) (Phormictopus pheopygus) 
2016-08-02 | PXD003884 | Pride
Data Access Committee EGAC00001000330
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