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TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon
This SuperSeries is composed of the following subset Series: GSE29704: Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [gene expression data] GSE29705: Two transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data] R...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29706 | biostudies-arrayexpress
TranscriptomicsInduction of target genes of AP2-Sp in AP2-O::Sp parasites
Sporozoite-specific genes were induced in parasites that express AP2-O whose AP2 domain was swapped with that of AP2-Sp. DNA construct encoding AP2 domain of AP2-Sp was introduced into P. bergei schizonts. It was integrated into the locus of the endogenious AP2-O gene, resulting in swap of the AP2-...
ORGANISM(S): Plasmodium berghei 
2010-06-20 | E-GEOD-18910 | biostudies-arrayexpress
TranscriptomicsTwo transcription factors are necessary for iron homeostasis in a salt-dwelling archaeon [ChIP-chip data]
Because iron toxicity and deficiency are equally life threatening, maintaining intracellular iron levels within a narrow optimal range is critical for nearly all known organisms. However, regulatory mechanisms that establish homeostasis are not well understood in organisms that dwell in environments...
ORGANISM(S): Halobacterium sp. NRC-1 
2011-06-02 | E-GEOD-29705 | biostudies-arrayexpress
TranscriptomicsCardiac transcription factors in HL-1 cells: gene expression and genome binding profiling
[1] Gene expression profiling in Gata4, Mef2a knockdown in HL-1 cells. HL-1 cells infected with adenovirus expressing either control siRNA or Gata4, and Gata4 & Mef2a siRNA. [2] Genome-wide maps of cardiac transcription factors binding region in HL-1 cells. We performed bio-ChIP-seq using streptavi...
ORGANISM(S): Mus musculus 
2011-03-02 | E-GEOD-21529 | biostudies-arrayexpress
TranscriptomicsGene expression patterns of sulfur starvation in Synechocystis sp. PCC 6803
The unicellular cyanobacterium Synechocystis sp. PCC 6803 is a model system for studying biochemistry, genetics and molecular biology of photobiological processes. Despite its importance in basic and applied research, the genome-wide picture of transcriptional regulation in this bacterium is limited...
ORGANISM(S): Synechocystis sp. PCC 6803 
2008-07-24 | E-GEOD-11970 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of time series of Cyanothece sp. ATCC 51142 grown in 12 hour light/12 hour dark cycle
Cyanothece sp. ATCC 51142 12 hour light / 12 hour dark 48 hour time course
ORGANISM(S): Cyanothece sp. ATCC 51142 
2008-07-11 | E-TABM-337 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of Cyanothece sp. grown in 12 hour light/12 hour dark then 24 h light
Cyanothece sp. ATCC 51142 12 hour light + 12 hour dark + 24 h light in a 48 hour time course
ORGANISM(S): Cyanothece sp. 
2008-07-11 | E-TABM-386 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bronchial epithelial cells overexpressing the lung developmental transcription factors TTF1, NKX2-8 and PAX9
We investigated the clinical implications of lung developmental transcription factors (TTF-1, NKX2-8, and PAX9) which we recently discovered as cooperating oncogenes activated by way of gene amplification at chromosome 14q13 in lung cancer. Using stable transfectants of human bronchial epithelial ce...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-9212 | biostudies-arrayexpress
TranscriptomicsPhotophysiological and Genetic Factors Underlying Fast Photosynthetic Growth of Unicellular Cyanobacterium Synechococcus sp. PCC 7002
Application of genome-scale 'omics approaches to dissect subcellular pathways and regulatory networks governing the fast-growing response of Synechococcus sp. PCC 7002 response to variable irradience levels. We employed controlled cultivation and next-generation sequencing technology to identify tra...
ORGANISM(S): Synechococcus sp. PCC 7942 
2015-09-04 | E-GEOD-72691 | biostudies-arrayexpress
TranscriptomicsCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Signaling through the thrombospondin-1 receptor CD47 broadly limits cell and tissue survival of stress, but the molecular mechanisms are incompletely understood. We now show that loss of CD47 permits sustained proliferation of primary murine endothelial cells and enables these cells to spontaneously...
ORGANISM(S): Mus musculus 
2013-07-10 | E-GEOD-43133 | biostudies-arrayexpress
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