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MetabolomicsIlluminating the dark space of neutral glycosphingolipidome by selective enrichment and profiling at multi-structural levels

Glycosphingolipids (GSLs) are essential components of cell membranes, particularly enriched in the nervous system. Altered molecular distributions of GSLs are increasingly associated with human diseases, emphasizing the significance of lipidomic profiling. Traditional GSL analysis methods are ham...

2024-06-25 | MTBLS10400 | MetaboLights
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells (part 2)
Recent RNA-sequencing studies have shown remarkable complexity in the mammalian transcriptome. The ultimate impact of this complexity on the predicted proteomic output is less well defined. We have undertaken a strand-specific RNA sequencing of multiple cellular RNA fractions (>18Gb) to uncover the ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-25842 | biostudies-arrayexpress
TranscriptomicsExposure of Deinococcus Radiodurans to 1126 Days in low Earth orbit: Molecular Patterns of Recovery after Tanpopo space Mission
Background: The International Space Station is an orbiting laboratory for microbial research in space, where microorganisms can be exposed to multiple extremes. Dehydrated cell clusters of extremophilic bacterium Deinococcus radiodurans have survived 3-year exposure outside the International Space S...
ORGANISM(S): Deinococcus radiodurans 
2025-02-27 | E-MTAB-13969 | biostudies-arrayexpress
ProteomicsMolecular repertoire of Deinococcus radiodurans after 1 year of exposure outside the International Space Station within the Tanpopo mission
Abstract Background The extraordinarily resistant bacterium Deinococcus radiodurans withstands harsh environmental conditions present in outer space. Deinococcus radiodurans was exposed for one year outside the International Space Station within Tanpopo orbital mission to investigate microbial surv...
ORGANISM(S): Deinococcus radiodurans R1 
2021-09-09 | PXD020047 | Pride
Molecular stress response Proteomics Metabolomics Deinococcus radiodurans Low earth orbit Transcriptomics 
UnknownSurface-enhanced Raman scattering sensors for biomedical and molecular detection applications in space.
Not available
S-EPMC7938280 | biostudies-literature
ProteomicsMapping of the local proteome of the Arabidopsis chloroplast intermembrane space by proximity labelling
The chloroplast intermembrane space, located between the outer and inner envelope membranes, plays key roles in protein and lipid trafficking. Currently, the proteome of the intermembrane space is largely uncharacterized, with only a relatively few protein players identified, and thus limiting our u...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-07-08 | PXD072271 | Pride
Ims Lc-msms Chloroplast 
UnknownSingle drop cytometry onboard the International Space Station.
Not available
S-EPMC10963801 | biostudies-literature
GenomicsSpace radiation induces distinct senescent phenotypes: Implications for space travel [scRNA-Seq]
Space radiation induces distinct senescent phenotypes: Implications for space travel [scRNA-Seq]
PRJNA1265193 | ENA
GenomicsSpace radiation induces distinct senescent phenotypes: Implications for space travel [bulk RNA-Seq]
Space radiation induces distinct senescent phenotypes: Implications for space travel [bulk RNA-Seq]
PRJNA1265190 | ENA
GenomicsA CRISPR-based assay for the study of eukaryotic DNA repair aboard the International Space Station
A CRISPR-based assay for the study of eukaryotic DNA repair aboard the International Space Station
PRJEB39039 | ENA
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