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ProteomicsIdentification of protein interactors of SPAG1 in human airway epithelia
Dysfunctional motile cilia result in primary ciliary dyskinesia (PCD), a genetically heterogeneous disorder characterized by chronic oto-sino-pulmonary disease, infertility, and laterality defects. Mutations in dynein axonemal assembly factors (DNAAF), that facilitate the assembly of dynein arms in ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-20 | PXD032349 | Pride
Cilia Affinity purification-mass spectrometry Spag1 
UnknownThe role of SPAG1 in the assembly of axonemal dyneins in human airway epithelia.
Not available
S-EPMC8995097 | biostudies-literature
UnknownMutations in SPAG1 cause primary ciliary dyskinesia associated with defective outer and inner dynein arms.
Not available
S-EPMC3791252 | biostudies-literature
UnknownComprehensive analysis of SPAG1 expression as a prognostic and predictive biomarker in acute myeloid leukemia by integrative bioinformatics and clinical validation.
Not available
S-EPMC8886923 | biostudies-literature
UnknownEstablishment of the early cilia preassembly protein complex during motile ciliogenesis.
Not available
S-EPMC5819421 | biostudies-literature
UnknownPromoter Deletion Leading to Allele Specific Expression in a Genetically Unsolved Case of Primary Ciliary Dyskinesia.
Not available
S-EPMC11698635 | biostudies-literature
UnknownCiliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP.
Not available
S-EPMC6028525 | biostudies-literature
UnknownDetection of novel and recurrent conjoined genes in non-Hodgkin B-cell lymphoma.
Not available
S-EPMC8265495 | biostudies-literature
UnknownThe RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones.
Not available
S-EPMC5974087 | biostudies-literature
UnknownDysregulated expression of mRNA and SNP in pulmonary artery remodeling in ascites syndrome in broilers.
Not available
S-EPMC7936122 | biostudies-literature
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